| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
We established novel methods to measure glucagon, GIP and GLP-1 beaded on cell-based receptor-mediated assays. We strongly speculate that these assays can reflect to physiological actions of those hormones through studies in vitro and in vivo, measuring samples during meal tolerance tests from non-dialect and diabetic subjects.
Furthermore, we established the method for selective collection of proglucagon-positive cells and identified glucagon expression in the gastrointestinal tract other than the pancreas.
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