| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
In the context of limited availability of antifungal agents, the emergence of multidrug resistant isolates has become a critical issue in clinical settings, underscoring an urgent need for the development of new antifungal strategies.
In this study, we have elucidated the resistant mechanisms of multidrug resistant Candida glabrata and the clinical and microbiological characteristics of Candida guilliermondii infections. In addition, we performed high-throughput screening of chemical compound libraries and found a novel compound that had potent antifungal activities.
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