Epidemiology and appropriate management of Staphylococcus aureus bacteremia
| Project/Area Number |
15K09577
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Infectious disease medicine
|
|---|
| Research Institution | Nara Medical University |
|---|
Principal Investigator |
Kei Kasahara 奈良県立医科大学, 医学部, 准教授 (50405403)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
矢野 寿一 奈良県立医科大学, 医学部, 教授 (20374944)
松元 加奈 同志社女子大学, 薬学部, 講師 (20469084)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
|---|
| Keywords | 黄色ブドウ球菌 / 菌血症 / 薬剤耐性 / MLST / 耐性菌 / MRSA |
|---|
| Outline of Final Research Achievements |
383 cases of Staphylococcus aureus bacteremia between 2008 and 2016 were evaluated. Cases of methicillin resistant Staphylococcus aureus (MRSA) were 219 (56.2%) and methicillin susceptible Staphylococcus aureus (MSSA) were 164 (42.8%). The most common POT (PCR-based open reading frame typing) among MRSA was 106-137-80 and the most common ST (sequence typing) among MSSA was ST188, followed by ST14.
The 30-day mortality of MRSA bacteremia was 23.4% and that of MSSA bacteremia was 16.1%. High pitt bacteremia score (PBS) and sequential organ failure assessment (SOFA) score was associated with higher mortality.
|
Report
(4 results)
Research Products
(21 results)
-
-
[Journal Article] Characteristics of health problems in returned overseas travelers at a tertiary teaching hospital in a suburban area in Japan2018
Author(s)
Hirata K, Ogawa T, Fujikura H, Ogawa Y, Hirai N, Nakagawa-Onishi T, Uno K, Takeyama M, Kasahara K, Nakamura(Uchiyama) F, Konishi M, Mikasa K
-
Journal Title
Journal of Infection and Chemotherapy
Volume: －
Related Report
Peer Reviewed
-
[Journal Article] The first multi-centre point-prevalence survey in four Japanese university hospitals2018
Author(s)
Morioka H, Nagao M, Yoshihara S, Ohge H, Kasahara K, Shigemoto N, Kajihara T, Mori M, Iguchi M, Tomita Y, Ichiyama S, Yagi T
-
Journal Title
Journal of Hospital Infection
Volume: －
Issue: 3
Pages: 325-331
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 維持透析中に細菌性髄膜炎を合併したMSSA咽後膿瘍・化膿性脊椎炎の一例2016
Author(s)
内藤 結花, 詫間 隆博, 前田 真之, 吉川 雅之, 宇賀神 和久, 田中 道子, 松元 加奈, 森田 邦彦, 石野 敬子, 二木 芳人, 加藤 大貴, 相馬 裕太, 工藤 理史, 佐々木 忠徳
Organizer
第65回日本感染症学会東日本地方会学術集会・ 第63回日本化学療法学会東日本支部総会
Place of Presentation
新潟市
Year and Date
2016-10-26
Related Report
-
-
-
-
-
-
