Neural foundation of resilience in PTSD: A MEG study using subliminal fearful face stimulus
| Project/Area Number |
15K09833
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | レジリエンス / PTSD / 自閉症スペクトラム障害 / うつ病 / 扁桃体 / 脳磁図 / 無意識 / 顔認知 / 高機能自閉症 / ＰＴＳＤ |
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| Outline of Final Research Achievements |
Amygdala is activated by anxiety and fear. PTSD, depression and ASD are suggested amygdala dysfunction. We hypothesized that fearful faces cause patients with PTSD who have low resilience overresponses of amygdala and cause persons with ASD low amygdala response. MEG can track the neural activities of amygdala with millisecond order. In depression, the resilience scale was sensitive to the symptom of depression and social support maybe a key role of sick recovery course. Regarding ASD,the responses in the left amygdala was weaker than those in the TD group's amygdala under the subliminal experimental condition.Therefore,there may be functional specialization between left and right amygdala.In the supraliminal experimental condition, there were no difference of amygdala responses between ASD and TD groups. Therefore, compensate mechanism can work during awareness process in the ASD.
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Report
(4 results)
Research Products
(19 results)
