| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Outline of Final Research Achievements |
In order to find out the effect evaluation index and the effect prediction index of cognitive behavior therapy (CBT), we measured the effect of CBT using clinical index and brain images. No significant difference was observed between the patients with social anxiety disorder (SAD) and the healthy controls in the region of interest (ROI) volumes of the prefrontal cortex, which were measured by manual parcellation and Freesurfer analyzation. In addition, no significant ROI volume changes were observed in the patients with SAD who received CBT. On the other hand, the brain activity in the frontal brain areas was less in the patients with autism spectrum disorder (ASD) than in subjects with typical development. Furthermore, the brain activity was positively associated with the improvement of the overall function of subjects with ASD caused by CBT. This might suggest that the frontal brain activity can be the effect prediction index of CBT.
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