The comprehensive study about psychosocial factors and nervous basis on the impulsivity of eating disorders
| Project/Area Number |
15K09864
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
上床 輝久 京都大学, 医学(系)研究科(研究院), その他 (20447973)
杉原 玄一 京都大学, 医学研究科, 助教 (70402261)
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| Research Collaborator |
YANASE Maya 京都大学, 大学院医学研究科, 助教
NODA Tomomi 京都大学, 大学院医学研究科, 客員研究員
MURAO Ema 京都大学, 大学院医学研究科, 客員研究員
ISOBE Masanori 京都大学, 大学院医学研究科, 客員研究員
KAWABATA Michiko 京都大学, 大学院医学研究科
MISHIMA Ryo 京都大学, 大学院医学研究科
TOSE Keima 京都大学, 大学院医学研究科
OONUMA Yoshihisa 東京大学, 大学院総合文化研究科
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 摂食障害 / 脳画像 / 感情制御 / 意思決定 / 窃盗 / 脳機能画像 / 報酬系 / 衝動性 / 自閉性 / 社会認知 |
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| Outline of Final Research Achievements |
On impulsivity of the patients with eating disorders, the brain image studies (Study A) and the investigation study of the prisoners because of theft (Study B) were conducted. The subjects of the Study A were the patients with eating disorders who were treated at the Kyoto University Hospital. The nervous activity levels of the patients with anorexia nervosa, binge/purging type during punishment anticipation task on the functional MRI were high. The nervous activity levels of the patients with anorexia nervosa, restricting type during reaction control task (GO-NOGO task) were activated. The scores of the Autisum Questionaire of the patients with anorexia nervosa were high. On the economic game task to estimate the ability of decision making, the rate of acceptance of unfair distribution of the patients with eating disorders was high. On the Study B, the thief behaviors occurred after the onset of the disease on 75% of the prisoners with eating disorders.
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Report
(4 results)
Research Products
(27 results)
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[Presentation] The Influence of Impulsivity and Personality Disorder Traits on Neural Processing of Reward and Punishment in Patients with Binge Eating and Purging: an fMRI Study2017
Author(s)
Toyoda-Murao, E., Isobe, M., Sugihara, G., Noda, T., Kawabata, M., Takahashi, H., Murai, T., Noma, S.
Organizer
International Conference on Eating Disorders
Related Report
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[Presentation] Autistic trait and functional connectivity in patients with anorexia nervosa2017
Author(s)
Kawabata-Nishida, M., Isobe, M., Murao, E., Noda, T., Takahashi, H., Murai, T., Noma, S.
Organizer
International Conference on Eating Disorders
Related Report
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[Presentation] The Relationship Between Shoplifting and Eating Disorders: Questionnaire Survey in Japanese Female Prison2017
Author(s)
Yanase, M., Sugihara, G., Morita, T., Yamasaki, H., Murai, T., Noma, S.
Organizer
International Conference on Eating Disorders
Related Report
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[Presentation] The neural bases of maladaptive coping style in eating disorders2017
Author(s)
Noda, T., Murao, E., Isobe, M., Kawabata, M., Sugihara, G., Murai, T., Noma, S.
Organizer
International Conference on Eating Disorders
Related Report
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[Presentation] Decision Making in Eating Behavior of Anorexia Nervosa Patients2017
Author(s)
Isobe, M., Murao, E., Kawabata, M., Noda, T., Mori, Y., Miyata, J., M., Fukuyama, H., Noma, S., Murai, T., Takahashi, H.
Organizer
第38回日本生物学的精神医学会
Related Report
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[Presentation] Functional Connectivity and Eating Attitude in Anorexia Nervosa2017
Author(s)
Isobe, M., Miyata, J., Mori, Y., Murao, E., Noda, T., Kawabata, M., Kozuki, H., Noma, S., Murai, T., Takahashi, H.
Organizer
第39回日本神経科学学会
Related Report
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[Presentation] Enhanced Coupling Between Salience Network and Basal Ganglia Network Predicts Distorted Eating Attitude in Anorexia Nervosa2017
Author(s)
Isobe, M., Mori, Y., Miyata, J., Fukuyama, H., Noma, S., Murai, T., Takahashi, H.
Organizer
Neuroscience
Related Report
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[Presentation] fMRIを用いた摂食障害患者における脳内報酬系の脳活動に関する研究2015
Author(s)
村尾英真,磯部昌憲,川端美智子,野田智美,松河理子,孫樹洛,鶴身孝介,川田良作, 杉原 玄一, 上床 輝久, 高橋 英彦, 村井 俊哉, 野間 俊一
Organizer
第111回日本精神神経学会学術総会
Place of Presentation
大阪
Year and Date
2015-06-04
Related Report
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