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The comprehensive study about psychosocial factors and nervous basis on the impulsivity of eating disorders

Research Project

Project/Area Number 15K09864
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Psychiatric science
Research InstitutionKyoto University

Principal Investigator

Noma Shun'ichi  京都大学, 医学研究科, 講師 (40314190)

Co-Investigator(Kenkyū-buntansha) 上床 輝久  京都大学, 医学(系)研究科(研究院), その他 (20447973)
杉原 玄一  京都大学, 医学研究科, 助教 (70402261)
Research Collaborator YANASE Maya  京都大学, 大学院医学研究科, 助教
NODA Tomomi  京都大学, 大学院医学研究科, 客員研究員
MURAO Ema  京都大学, 大学院医学研究科, 客員研究員
ISOBE Masanori  京都大学, 大学院医学研究科, 客員研究員
KAWABATA Michiko  京都大学, 大学院医学研究科
MISHIMA Ryo  京都大学, 大学院医学研究科
TOSE Keima  京都大学, 大学院医学研究科
OONUMA Yoshihisa  東京大学, 大学院総合文化研究科
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords摂食障害 / 脳画像 / 感情制御 / 意思決定 / 窃盗 / 脳機能画像 / 報酬系 / 衝動性 / 自閉性 / 社会認知
Outline of Final Research Achievements

On impulsivity of the patients with eating disorders, the brain image studies (Study A) and the investigation study of the prisoners because of theft (Study B) were conducted. The subjects of the Study A were the patients with eating disorders who were treated at the Kyoto University Hospital. The nervous activity levels of the patients with anorexia nervosa, binge/purging type during punishment anticipation task on the functional MRI were high. The nervous activity levels of the patients with anorexia nervosa, restricting type during reaction control task (GO-NOGO task) were activated. The scores of the Autisum Questionaire of the patients with anorexia nervosa were high. On the economic game task to estimate the ability of decision making, the rate of acceptance of unfair distribution of the patients with eating disorders was high. On the Study B, the thief behaviors occurred after the onset of the disease on 75% of the prisoners with eating disorders.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (27 results)

All 2017 2016 2015

All Journal Article (6 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results) Presentation (21 results)

  • [Journal Article] Shoplifting and eating disorders: an anonymous self-administered survey2017

    • Author(s)
      Yanase Maya、Sugihara Genichi、Murai Toshiya、Noma Shun’ichi
    • Journal Title

      Eat Weight Disord.

      Volume: 1 Issue: 6 Pages: 1-7

    • DOI

      10.1007/s40519-017-0394-9

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Differences in neural responses to reward and punishment processing between anorexia nervosa subtypes : An fMRI study2017

    • Author(s)
      Murao E, Sugihara G, Isobe M, Noda T, Kawabata M, Matsukawa N, Takahashi H, Murai T, Noma S
    • Journal Title

      Psychiatry and Clinical Neurosciences

      Volume: 71 Issue: 9 Pages: 647-658

    • DOI

      10.1111/pcn.12537

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 摂食障害の診断と評価2017

    • Author(s)
      野間 俊一
    • Journal Title

      日本医師会雑誌

      Volume: 146 Pages: 1535-1538

    • Related Report
      2017 Annual Research Report
  • [Journal Article] 過食の病理とメカニズム2016

    • Author(s)
      野間俊一 村井俊哉
    • Journal Title

      実験医学

      Volume: 34 Pages: 120-124

    • Related Report
      2016 Research-status Report
  • [Journal Article] 嗜癖の観点からみた摂食障害2016

    • Author(s)
      野間俊一
    • Journal Title

      臨床精神医学

      Volume: 45 Pages: 1565-1569

    • Related Report
      2016 Research-status Report
  • [Journal Article] 和歌山刑務所における窃盗癖の実際と摂食障害2016

    • Author(s)
      梁瀬まや 杉原玄一 森田貴子 山崎浩 村井俊哉 野間俊一
    • Journal Title

      臨床精神医学

      Volume: 45 Pages: 1577-1583

    • Related Report
      2016 Research-status Report
  • [Presentation] 過食排出を伴う摂食障害患者の脳内報酬系における多衝動性の影響2017

    • Author(s)
      村尾英真、磯部昌憲、川端美智子、野田智美、野間俊一
    • Organizer
      第19回日本ヒト脳機能マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2017-03-09
    • Related Report
      2016 Research-status Report
  • [Presentation] 神経性やせ症患者における自閉症スペクトラム傾向と脳機能的結合の関連2017

    • Author(s)
      川端美智子、磯部昌憲、村尾英真、野田智美、高橋英彦、野間俊一
    • Organizer
      第19回日本ヒト脳マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2017-03-09
    • Related Report
      2016 Research-status Report
  • [Presentation] 摂食障害患者における非適応的コーピングスタイルの神経基盤2017

    • Author(s)
      野田智美、村尾英真、磯部昌憲、川端美智子、杉原玄一、高橋英彦、村井俊哉、野間俊一
    • Organizer
      第19回日本ヒト脳機能マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2017-03-09
    • Related Report
      2016 Research-status Report
  • [Presentation] The Influence of Impulsivity and Personality Disorder Traits on Neural Processing of Reward and Punishment in Patients with Binge Eating and Purging: an fMRI Study2017

    • Author(s)
      Toyoda-Murao, E., Isobe, M., Sugihara, G., Noda, T., Kawabata, M., Takahashi, H., Murai, T., Noma, S.
    • Organizer
      International Conference on Eating Disorders
    • Related Report
      2017 Annual Research Report
  • [Presentation] Autistic trait and functional connectivity in patients with anorexia nervosa2017

    • Author(s)
      Kawabata-Nishida, M., Isobe, M., Murao, E., Noda, T., Takahashi, H., Murai, T., Noma, S.
    • Organizer
      International Conference on Eating Disorders
    • Related Report
      2017 Annual Research Report
  • [Presentation] The Relationship Between Shoplifting and Eating Disorders: Questionnaire Survey in Japanese Female Prison2017

    • Author(s)
      Yanase, M., Sugihara, G., Morita, T., Yamasaki, H., Murai, T., Noma, S.
    • Organizer
      International Conference on Eating Disorders
    • Related Report
      2017 Annual Research Report
  • [Presentation] The neural bases of maladaptive coping style in eating disorders2017

    • Author(s)
      Noda, T., Murao, E., Isobe, M., Kawabata, M., Sugihara, G., Murai, T., Noma, S.
    • Organizer
      International Conference on Eating Disorders
    • Related Report
      2017 Annual Research Report
  • [Presentation] Decision Making in Eating Behavior of Anorexia Nervosa Patients2017

    • Author(s)
      Isobe, M., Murao, E., Kawabata, M., Noda, T., Mori, Y., Miyata, J., M., Fukuyama, H., Noma, S., Murai, T., Takahashi, H.
    • Organizer
      第38回日本生物学的精神医学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Functional Connectivity and Eating Attitude in Anorexia Nervosa2017

    • Author(s)
      Isobe, M., Miyata, J., Mori, Y., Murao, E., Noda, T., Kawabata, M., Kozuki, H., Noma, S., Murai, T., Takahashi, H.
    • Organizer
      第39回日本神経科学学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Enhanced Coupling Between Salience Network and Basal Ganglia Network Predicts Distorted Eating Attitude in Anorexia Nervosa2017

    • Author(s)
      Isobe, M., Mori, Y., Miyata, J., Fukuyama, H., Noma, S., Murai, T., Takahashi, H.
    • Organizer
      Neuroscience
    • Related Report
      2017 Annual Research Report
  • [Presentation] 経済ゲームを用いた摂食障害患者の意思決定研究-脳MRI画像を用いた神経科学的検討-2017

    • Author(s)
      大沼慶寿、磯部昌憲、野田智美、村尾英真、川端美智子、三木寛隆、早瀬允人、高橋英彦、村井俊哉、野間俊一
    • Organizer
      第21回日本摂食障害学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 摂食障害治療における精神科と他科との理想的な連携について2017

    • Author(s)
      野間俊一
    • Organizer
      第46回日本女性心身医学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 大学病院での摂食障害臨床と地域支援2017

    • Author(s)
      野間俊一
    • Organizer
      第21回日本摂食障害学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 摂食障害における自己愛の構造と精神療法2016

    • Author(s)
      野間俊一
    • Organizer
      第39回日本精神病理学会
    • Place of Presentation
      浜松
    • Year and Date
      2016-10-07
    • Related Report
      2016 Research-status Report
  • [Presentation] fMRIを用いた摂食障害患者における脳内報酬系の脳活動に関する研究2016

    • Author(s)
      村尾英真, 磯部昌憲, 川端美智子, 野田智美, 松河理子, 杉原 玄一, 上床 輝久, 高橋 英彦, 村井 俊哉, 野間 俊一
    • Organizer
      第18回日本ヒト脳機能マッピング学会
    • Place of Presentation
      京都
    • Year and Date
      2016-03-07
    • Related Report
      2015 Research-status Report
  • [Presentation] fMRIを用いた摂食障害患者における脳内報酬系の脳活動に関する研究2015

    • Author(s)
      豊田(村尾)英真,磯部昌憲,川端美智子,野田智美,松河理子,杉原 玄一, 上床 輝久, 高橋 英彦, 村井 俊哉, 野間 俊一
    • Organizer
      第19回日本摂食障害学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 社会的場面における摂食障害患者の意思決定2015

    • Author(s)
      磯部昌憲、川端美智子、村尾英真、上月遥、野田智美、松河理子、村井俊哉、高橋英彦、野間俊一
    • Organizer
      第19回日本摂食障害学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 摂食障害患者における反応抑制の神経基盤2015

    • Author(s)
      野田智美 磯部昌憲 村尾英真 川端美智子 松河理子 上床輝久 杉原玄一 高橋英彦 村井俊哉  野間俊一
    • Organizer
      第19回日本摂食障害学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-24
    • Related Report
      2015 Research-status Report
  • [Presentation] 摂食障害患者の対人場面における意思決定2015

    • Author(s)
      磯部昌憲、川端美智子、野間俊一
    • Organizer
      第56回日本心身医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-26
    • Related Report
      2015 Research-status Report
  • [Presentation] fMRIを用いた摂食障害患者における脳内報酬系の脳活動に関する研究2015

    • Author(s)
      村尾英真,磯部昌憲,川端美智子,野田智美,松河理子,孫樹洛,鶴身孝介,川田良作, 杉原 玄一, 上床 輝久, 高橋 英彦, 村井 俊哉, 野間 俊一
    • Organizer
      第111回日本精神神経学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2015-06-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 摂食障害患者の社会的意思決定 -経済ゲームを用いた検討-2015

    • Author(s)
      磯部昌憲、村尾英真、川端美智子、松河理子、野田智美、宮田淳、杉原玄一、村井俊哉、高橋英彦、野間俊一
    • Organizer
      第111回日本精神神経学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2015-06-04
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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