Research for comprehensive assessment for comorbidities associated with ASD

• Project/Area Number: 15K09879
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Psychiatric science
• Research Institution: National Center of Neurology and Psychiatry
• Principal Investigator: ISHITOBI MAKOTO 国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 児童・思春期精神保健研究部, 室長 (50464053)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
• Keywords: 自閉症 / 併存症 / ASD / BISCUIT / 自閉スペクトラム症 / 自閉症スペクトラム障害

Outline of Final Research Achievements

We investigated comorbidities related with ASD for elementary school children using questionnaire. Children with high autistic trait have high referral rate to assistance service and parents had already concerns about comorbid problems as well as autistic symptoms from early childhood. We also investigated comorbidities related with ASD for infants with ASD using BISCUIT-J(PART2,3), which aseesees comorbid problems, and showed that comorbid problems are already detected in this early age.

Research Products

• [Journal Article] Examining cross-cultural differences in autism spectrum disorder: A multinational comparison from Greece, Italy, Japan, Poland, and the United States. (2017)
  • Author(s): J.L. Matson , M. Matheis, C.O. Burns, G. Esposito, P. Venuti, E. Pisula , A. Misiak, E. Kalyva, V. Tsakiris, Y. Kamio, M. Ishitobi, R.L. Goldin.
  • Journal Title: European Psychiatry Volume: 42 Pages: 70-76
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Current viewpoints on DSM-5 in Japan. (2016)
  • Author(s): Kuroki T, Ishitobi M, Kamio Y, Sugihara G, Murai T, Motomura K, Ogasawara K, Kimura H, Aleksic B, Ozaki N, Nakao T, Yamada K, Yoshiuchi K, Kiriike N, Ishikawa T, Kubo Ch, Matsunaga C, Miyata H, Asada T, Kanba S.
  • Journal Title: Psychiatry and Clinical Neuroscience Volume: 70(9) Pages: 371-93
  • Peer Reviewed
• [Journal Article] Altered frontal pole development affects self-generated spatial working memory in ADHD (2016)
  • Author(s): Sumiyoshi ARAI, Yuko OKAMOTO, Toru FUJIOKA, Keisuke INOHARA, Makoto ISHITOBI, Yukiko MATSUMURA et al
  • Journal Title: Brain & Development Volume: 38 Pages: 471-80
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Neural correlates of emotion processing during observed self-face recognition in individuals with autism spectrum disorders Research in Autism Spectrum Disorders (2016)
  • Author(s): 2.Tomoyo Morita , Hirotaka Kosaka, Daisuke N. Saito, Takeshi Fujii, Makoto Ishitobi, Toshio Munesue, Keisuke Inohara, Hidehiko Okazawa, Ryusuke Kakigi, Norihiro Sadato.
  • Journal Title: Research in Autism Spectrum Disorders Volume: 26 Pages: 16-32
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] The Baby and Infanat Screen for Children with aUtIsm Traits (BUSCUIT)日本語版による自閉症スペクトラム障害の併存症の早期評価 (2016)
  • Author(s): 石飛信, 山口穂菜美, 神尾陽子
  • Organizer: 第57回日本児童精神医学会総会
  • Place of Presentation: 岡山
  • Year and Date: 2016-10-27
• [Presentation] 自閉症スペクトラム障害と治療反応性 (2016)
  • Author(s): 神尾陽子, 石飛信, 原口英之
  • Organizer: 第112回日本精神神経学会学術総会
  • Place of Presentation: 千葉
  • Year and Date: 2016-06-02
  • Invited
• [Presentation] 自閉症特性と併存症の関連性に関する研究～地域コホートにおける予備的検討 (2015)
  • Author(s): 6.石飛信、小原由香、原口英之、荻野和雄、高橋秀俊、野中俊介、神尾陽子
  • Organizer: 第56回日本児童青年精神医学会総会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2015-09-29
• [Book] データで読み解く発達障害 (2016)
  • Author(s): 石飛信、小坂浩隆、神尾陽子
  • Publisher: 中山書店