Patient organ doses from CT based on absorbed dose-to-water dosimetry using cylindrical water phantoms.

• Project/Area Number: 15K09897
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Kumamoto University
• Principal Investigator: Araki Fujio 熊本大学, 大学院生命科学研究部(保), 教授 (00295148)
• Co-Investigator(Kenkyū-buntansha): 大野 剛 熊本大学, 大学院生命科学研究部(保), 助教 (20646971)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: Multi-detector CT / Monte Carlo simulation / CT dosimetry / organ dose / 被ばく線量 / X-CT / 自動露出機構 / モンテカルロ計算 / 線量分布計算 / Multi detector / 電離量測定 / X線CT / モンテカルロ法 / 吸収線量計測 / 線量体積ヒストグラム / 電離箱測定 / 線質変換係数 / コバルト水吸収線量校正定数

Outline of Final Research Achievements

In this study, we evaluated patient organ dose based on absorbed water-to-dose measurements using cylindrical water phantoms. (1) The sources for four commercial MDCT scanners were modeled with the Monte Carlo method based on Al-attenuation curves and lateral dose profiles in free air. (2) The absorbed dose to water in cylindrical water phantoms was measured with a Farmer-type ionization chamber and was calculated by Monte Carlo method (3) The patient organ dose was calculated from dose volume histograms obtained by the Monte Carlo method using CT images. (4) The reduction of the exposure dose investigated by simulating a tube-current modulation technique using the Monte Carlo method.

Research Products

• [Journal Article] Image quality of four-dimensional cone-beam computed tomography obtained at various gantry rotation speeds for liver stereotactic body radiation therapy with fiducial markers (2018)
  • Author(s): Shimohigashi Yoshinobu、Araki Fujio、Maruyama Masato、Yonemura Keisuke、Nakaguchi Yuji、Kai Yudai、Toya Ryo
  • Journal Title: Physica Medica Volume: 45 Pages: 19-24
  • DOI: 10.1016/j.ejmp.2017.11.020
  • Peer Reviewed / Open Access
• [Journal Article] Identification of elemental weight fraction and mass density of humanoid tissue-equivalent materials using dual energy computed tomography (2017)
  • Author(s): Kohei Shimomura, Fujio Araki, Fujio ArakiEmail the author Fujio Araki, Yuki Kono, Yoshiyuki Asai, Takamichi Murakami, Tomoko Hyodo, Masahiko Okumura, Kenji Matsumoto, Hajime Monzen, Yasumasa Nishimura
  • Journal Title: Physica Medica: European Journal of Medical Physics Volume: 39 Pages: 59-66
  • DOI: 10.1016/j.ejmp.2017.05.060
  • Peer Reviewed / Open Access
• [Journal Article] Dosimetric properties of a Solid Water High Equivalency (SW557) phantom for megavoltage photon beams (2017)
  • Author(s): Fujio Araki
  • Journal Title: Physica Medica Volume: 39 Pages: 132-136
  • DOI: 10.1016/j.ejmp.2017.06.011
  • Peer Reviewed
• [Journal Article] Comparison of dosimetric properties among four commercial multi-detector computed tomography scanners (2017)
  • Author(s): Takeshi Ohno, Fujio Araki, Ryota Onizuka et al.
  • Journal Title: Physica Medica Volume: 35 Pages: 50-58
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Tumor motion changes in stereotactic body radiotherapy for liver tumors: Evaluation based on four-dimensional cone-beam computed tomography and fiducial markers (2017)
  • Author(s): Yoshinobu Shimohigashi, Rto Toya, Fujio Araki et al.
  • Journal Title: Radiation Oncology Volume: 12:61 Pages: 1-8
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Accuracy of dose calculation algorithms for virtual heterogeneous phantoms and intensity-modulated radiation therapy in the head and neck (2016)
  • Author(s): Ryota Onizuka, Fujio Araki, Takeshi Ohno, Yuji Nakaguchi, Yudai Kai, Yuuki Tomiyama, and Kazunari Hioki
  • Journal Title: Radiological Physics and Technology Volume: 9 Issue: 1 Pages: 77-87
  • DOI: 10.1007/s12194-015-0336-z
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] New absorbed dose measurement with cylindrical water phantoms for multidetector CT (2015)
  • Author(s): Takeshi Ohno, Fujio Araki, Ryota Onizuka ,Kazunari Hioki, Yuuki Tomiyama, and Yusuke Yamashita
  • Journal Title: Physics in Medicine and Biology Volume: 60 Issue: 11 Pages: 4517-4531
  • DOI: 10.1088/0031-9155/60/11/4517
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Monte Carlo-calculated patient organ doses from kV-cone beam CT in image-guided radiation therapy (2015)
  • Author(s): Kazunari Hioki, Fujio Araki, Takeshi Ohno, Yuuki Tomiyama and Yuji Nakaguchi
  • Journal Title: Biolmedical Physics and Engineering Express Volume: 1 Issue: 2 Pages: 025203-025203
  • DOI: 10.1088/2057-1976/1/2/025203
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Absorbed dose-to-water measurement of an HDR 192Ir source with Farmer ionization chambers in a sandwich setup (2015)
  • Author(s): Fujio Araki, Takeshi Ohno, Kiyotaka Kakei and Shinji Kawamura
  • Journal Title: Biolmedical Physics and Engineering Express Volume: 1 Issue: 3 Pages: 037002-037002
  • DOI: 10.1088/2057-1976/1/3/037002
  • Peer Reviewed / Acknowledgement Compliant
• [Presentation] Comparison of absorbed Dose Based On Air-Kerma Calibration and 60Co Absorbed-Dose Calibration in Diagnostic X-Ray Beams (2017)
  • Author(s): F Araki, S Umeno, T Ohno,
  • Organizer: 2017 AAPM Annual Meeting
  • Int'l Joint Research
• [Presentation] PHITS Monte Carlo Dose-Verification of VMAT Treatment Plan with HD120MLC (2017)
  • Author(s): N Nagaishi, F Araki, T Ohno
  • Organizer: 2017 AAPM Annual Meeting
  • Int'l Joint Research
• [Presentation] Reduction of Normal Brain Dose by Optimizing Irradiation Angles for VMAT in Multiple Brain Metastases (2017)
  • Author(s): N Yamaura, F Araki, T Ohno
  • Organizer: 2017 AAPM Annual Meeting
  • Int'l Joint Research
• [Presentation] Image Quality of 4D-CBCT with Varying Gantry Rotation Speeds for Liver SBRT with Fiducial Markers (2017)
  • Author(s): Y Shimohigashi, R Toya, F Araki et al.
  • Organizer: 2017 AAPM Annual Meeting
  • Int'l Joint Research
• [Presentation] New dosimetry based on 60Co absorbed dose-to-water calibration in diagnostic x-ray beams. (2017)
  • Author(s): Suzuna Umeno, Fujio Araki, Takeshi Ohno
  • Organizer: Proceedings of the 113th Scientific Meeting of JSMP
• [Presentation] Dosimetric accuracy of dose calculation algorithms for VMAT in multiple brain metastases (2017)
  • Author(s): Kento Hoshida, Fujio Araki, Takeshi Ohno et al.
  • Organizer: Proceedings of the 113th Scientific Meeting of JSMP
• [Presentation] A comparison between dose calculation algorithms for VMAT-SBRT plans in lung tumor (2017)
  • Author(s): Takanori Matsuoka, Fujio Araki, Takeshi Ohno
  • Organizer: Proceedings of the 113th Scientific Meeting of JSMP
• [Presentation] Effect of transverse magnetic fields on dose distributions of photon beams in Geant4 (2017)
  • Author(s): Takanori Matsuoka, Fujio Araki, Takeshi Ohno
  • Organizer: Proceedings of the 114th Scientific Meeting of JSMP
  • Int'l Joint Research
• [Presentation] The response of a nanoDot OSLD system in megavoltage photon beams (2017)
  • Author(s): Kento Hoshida, Fujio Araki, Takeshi Ohno et al.
  • Organizer: Proceedings of the 114th Scientific Meeting of JSMP
  • Int'l Joint Research
• [Presentation] Evaluation of entrance surface dose using a dose area product meter in diagnostic x-ray beams (2017)
  • Author(s): Suzuna Umeno, Fujio Araki, Takeshi Ohno
  • Organizer: Proceedings of the 114th Scientific Meeting of JSMP
  • Int'l Joint Research
• [Presentation] Combined Organ Dose for Digital Subtraction Angiography and Computed Tomography Using Monte Carlo Simulation (2016)
  • Author(s): D Sakabe, T Ohno, F Araki et al
  • Organizer: 2016 AAPM Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] Monte Carlo-Dose Verification of Volumetr ic Modulated Arc Therapy Plans Using AAPM TG-119 Test Patterns (2016)
  • Author(s): R Onizuka, F Araki, T Ohno et al.
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] Monte Carlo Dose Verification for Volumetric Modulated Arc Therapy in Multiple Brain Metastases (2016)
  • Author(s): H Tominaga, F Araki, N Kanetake, J Sakata
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] The effect of Inter-Seed Attenuation and Tissue Composition in Prostate 1251 Brachytherapy Dose Calculations (2016)
  • Author(s): K Tamura, F Araki , T Ohno
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] Impact of VMAT Dose Calculations with Respiratory Movements in Lung (2016)
  • Author(s): K Komatsu, F Araki, T Ohno et al.
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] Evaluation of I nterfractional and Intrafractional Tumor Motion in Stereotactic Liver Radiotherapy, Based On Four-Dimensional Cone-Beam Computed Tomography Using Fiducial Markers (2016)
  • Author(s): Y Shimohigashi, F Araki, R Toya et al.
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] Comparison of Performance of Tube-Current Modulation of Three Commercial MDCT Scanners (2016)
  • Author(s): Takeshi Ohno and Fujio Araki
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] New ionization chamber dosimetry of absorbed dose to water in diagnostic kV x-ray beams (2016)
  • Author(s): Fujio Araki and Takeshi Ohno
  • Organizer: 2016 American Association of Physicists in Medicine Annual Meeting
  • Place of Presentation: WASHINGTON, DC, USA
  • Int'l Joint Research
• [Presentation] CTの吸収線量測定法の確立と患者臓器線量の定量的評 (2015)
  • Author(s): 大野 剛，荒木 不次男，羽手村 昌宏，下之坊 俊明，他
  • Organizer: 第43回日本放射線技術学会秋季学術大会
  • Place of Presentation: 金沢市
  • Year and Date: 2015-10-08
• [Presentation] Monte Carlo-dose verification of volumetric modulated arc therapy plans for AAPM TG-119 test patterns (2015)
  • Author(s): Ryota Onizuka, Fujio Araki, Takeshi Oono, and Yuji Nakaguthi
  • Organizer: Proceeding of the 110th Scientific Meeting of JSMP
  • Place of Presentation: 札幌市
  • Year and Date: 2015-09-19
• [Presentation] Dose verification using three-dimensional gamma analysis for volumetric modulated arc therapy in multiple brain metastases (2015)
  • Author(s): Hirofumi Tominaga, Fujio Araki, Ryota Oniduka, Shingo Tajiri, Nagisa Kanetake and Junichi Sakata
  • Organizer: Proceeding of the 110th Scientific Meeting of JSMP
  • Place of Presentation: 札幌市
  • Year and Date: 2015-09-19
• [Presentation] Comparison of beam characteristics and organ dose from four commercial multidetector computed tomography scanners (2015)
  • Author(s): Takeshi Ohno annd Fujio Araki
  • Organizer: 2015 AAPM Annual Meeting
  • Place of Presentation: Anaheim, CA, USA
  • Year and Date: 2015-07-12
  • Int'l Joint Research
• [Presentation] Dosimetric properties of a new solid water high equivalency phantom for high-energy photon beams (2015)
  • Author(s): Fujio Araki, Takeshi Ohno, Ryota Onitsuka, and Yoshinobu Shimohigashi
  • Organizer: 2015 AAPM Annual Meeting
  • Place of Presentation: Anaheim, CA, USA
  • Year and Date: 2015-07-12
  • Int'l Joint Research
• [Presentation] Dosimetric comparison between four types of computed tomography units (2015)
  • Author(s): Takeshi Oono, Fujio Araki, Masahiro Hatemura, Toshiaki Shimonobou, Takashi Sakamoto, Shuichiro Okumura, Daichi Ideguchi, Keiichi Honda, Kenji Kawata, Takehiro Kuroda
  • Organizer: Proceeding of the 109th Scientific Meeting of JSMP
  • Place of Presentation: 横浜市
  • Year and Date: 2015-04-16
• [Presentation] Monte Carlo study of VMAT dose distributions from an Elekta Synergy integrating the Agility 160-leaf multileaf collimator (2015)
  • Author(s): Ryota Onizuka, Fujio Araki, Takeshi Oono, Yuji Nakaguthi, Yoshinobu Shimohigashi
  • Organizer: Proceeding of the 109th Scientific Meeting of JSMP
  • Place of Presentation: 横浜市
  • Year and Date: 2015-04-16