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Observation of porcine liver vessels by X-ray phase contrast image

Research Project

Project/Area Number 15K09900
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionIbaraki Prefectural University of Health Science

Principal Investigator

MORI KOICHI  茨城県立医療大学, 保健医療学部, 教授 (90274977)

Co-Investigator(Kenkyū-buntansha) 大久保 知幸  茨城県立医療大学, 保健医療学部, 助教 (30704605)
関根 紀夫  首都大学東京, 人間健康科学研究科, 准教授 (70295434)
小原 弘道  首都大学東京, 理工学研究科, 准教授 (80305424)
中島 修一  茨城県立医療大学, 保健医療学部, 助教 (00735061)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords位相コントラスト / 放射光 / 肝臓 / 小葉 / 豚 / X線 / 循環 / 放射線技術学 / 類洞 / 肝小葉 / 中心静脈 / 血管造影 / 血管 / 位相イメージング
Outline of Final Research Achievements

This experiment was performed at Synchrotron Radiation Research Facility (KEKPF). Images of blood vessels were taken by X-ray phase contrast method. Four specimens of pig liver of 2-3 months old and about 20 kg body weight were used. Warm ischemic time of the samples were 0 or 60 minutes. Simple chilling at 4 to 10 °C for 2 to 4 hours, then the liver preservation solution was perfused for about 2 hours. For describing the hepatic lobule, an ultrasonic contrast medium was used. A granular structure appeared in the image about 1-2 hours after injection of the contrast medium from the portal vein or the hepatic artery. Its shape was polygonal or nearly circular. One granular structure is considered to correspond to one hepatic lobule.We succeeded in depicting hepatic lobules by this technique.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2017 2016 2015

All Presentation (6 results)

  • [Presentation] MTFチャートを用いたX線位相コントラスト画像法の解像特性評価の試み2017

    • Author(s)
      関根紀夫,森 浩一,小原弘道,中島修一,藤井義大,中野渡 滉希,兵藤一行
    • Organizer
      第27 回日本保健科学学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 放射光X線を用いた位相コントラスト法による肝臓内血管流動特性の可視化2016

    • Author(s)
      小原弘道
    • Organizer
      日本機械学会2016年度年次大会
    • Place of Presentation
      九州大学伊都キャンパス
    • Year and Date
      2016-09-11
    • Related Report
      2016 Research-status Report
  • [Presentation] 放射光X線を用いた位相コントラスト法による肝末梢血管系の描画2016

    • Author(s)
      森 浩一
    • Organizer
      第26回日本保健科学学会学術集会
    • Place of Presentation
      目白大学新宿キャンパス「研心館」
    • Related Report
      2016 Research-status Report
  • [Presentation] X線位相コントラスト画像法の軟組織における解像特性評価の試み2016

    • Author(s)
      関根紀夫
    • Organizer
      第26回日本保健科学学会学術集会
    • Place of Presentation
      目白大学新宿キャンパス「研心館」
    • Related Report
      2016 Research-status Report
  • [Presentation] 放射光X線を用いた位相コントラスト法による豚肝臓血管の観察2015

    • Author(s)
      森 浩一
    • Organizer
      第43回日本放射線技術学会秋季学術大会
    • Place of Presentation
      金沢市文化ホール
    • Year and Date
      2015-10-09
    • Related Report
      2015 Research-status Report
  • [Presentation] 放射光X線を用いた位相コントラスト法による肝動脈の描写2015

    • Author(s)
      関根紀夫
    • Organizer
      第25回日本保健科学学会学術集会
    • Place of Presentation
      首都大学東京荒川キャンパス
    • Year and Date
      2015-09-26
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2025-01-30  

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