• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Novel development of non-invasive imaging for peripheral arterial occlusive disease

Research Project

Project/Area Number 15K09902
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionIwate Medical University

Principal Investigator

Tanaka Ryoichi  岩手医科大学, 医学部, 准教授 (30393218)

Co-Investigator(Renkei-kenkyūsha) YOSHIOKA Kunihiro  岩手医科大学, 医学部, 教授 (70210648)
SUZUKI Michiko  岩手医科大学, 医学部, 助教 (10740780)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsCT / サブトラクション / 閉塞性動脈疾患 / 動脈硬化 / CT angiography / 閉塞性動脈硬化症 / 画像診断 / Computed Tomography / 血管造影
Outline of Final Research Achievements

We developed novel non-invasive imaging using computed tomographic angiography (CTA) for evaluating peripheral arterial occlusive disease caused by arteriosclerosis. In this study, we especially focused on the accuracy in detecting severe stenosis within the lesion surrounded by the arterial wall calcification, and we developed the technique named “subtraction CTA”.
In comparison with invasive angiography, subtraction CTA had high correlation in detecting lesion severity and its diagnostic accuracy was 89%. Remarkably, in cases of critical limb ischemia, the diagnostic accuracy of subtraction CTA was 94.6%.
We also evaluated the utility of ultra-high resolution computed tomography (CT) in detecting lesions at smaller caliber arteries such as digital arteries of the foot. Subtraction CTA technique was also available in the use of ultra-high resolution CT, non-invasive visualization of digital artery of the foot was feasibly achieved.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2018 2016 2015

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results) (of which Int'l Joint Research: 1 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Journal Article] Novel developments in non-invasive imaging of peripheral arterial disease with CT: experience with state-of-the-art, ultra-high-resolution CT and subtraction imaging2018

    • Author(s)
      Tanaka R.、Yoshioka K.、Takagi H.、Schuijf J.D.、Arakita K.
    • Journal Title

      Clinical Radiology

      Volume: 印刷中 Issue: 1 Pages: 51-58

    • DOI

      10.1016/j.crad.2018.03.002

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Subtraction CT angiography for the diagnosis of iliac arterial steno-occlusive disease2016

    • Author(s)
      Suzuki, M., Tanaka, R., Yoshioka, K., Abiko, A., Ehara, S
    • Journal Title

      Japanese Journal of Radiology

      Volume: 34 Issue: 3 Pages: 194-202

    • DOI

      10.1007/s11604-015-0508-0

    • NAID

      210000183886

    • Related Report
      2016 Research-status Report 2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Evaluation of peripheral arterial diseases using ultra-high resolution CT2016

    • Author(s)
      Ryoichi Tanaka, Kunihiro Yoshioka, Hidenobu Takagi, Shigeru Ehara
    • Organizer
      102nd Scientific Assembly and Annual Meeting of Radiological Society of North America (RSNA 2016)
    • Place of Presentation
      Chicago
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Patent(Industrial Property Rights)] United States Patent2015

    • Inventor(s)
      Ryoichi Tanaka, et al.
    • Industrial Property Rights Holder
      Iwate Medical University, et al.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-05-28
    • Acquisition Date
      2017-02-07
    • Related Report
      2016 Research-status Report
    • Overseas

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi