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Chemical exchange saturation transfer (CEST) imaging of head and neck tumor

Research Project

Project/Area Number 15K09928
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Radiation science
Research InstitutionKyushu University

Principal Investigator

Kamitani Takeshi  九州大学, 大学病院, 助教 (20419534)

Co-Investigator(Kenkyū-buntansha) 川波 哲  九州大学, 大学病院, 助教 (50330999)
長尾 充展  九州大学, 医学研究院, 准教授 (60533081)
栂尾 理  九州大学, 大学病院, 助教 (10452749)
山崎 誘三  九州大学, 大学病院, その他 (00643347)
山之内 寅彦  独立行政法人国立病院機構別府医療センター(臨床研究部), 臨床研究部, その他 (40748034)
藪内 英剛  九州大学, 医学研究院, 教授 (70380623)
日野 卓也  九州大学, 大学病院, 医員 (10807100)
亀井 俊佑  九州大学, 大学病院, 医員 (90778862)
進 政太郎  九州大学, 大学病院, 医員 (10794224)
本田 浩  九州大学, 大学病院, 教授 (90145433)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords耳下腺 / MRI / CEST / APT / 耳下腺腫瘍
Outline of Final Research Achievements

The mean amide proton transfer (APT) signal intensity of malignant parotid tumors was significantly higher than that of benign parotid tumors. Most of the malignant tumors showed APT signal intensities of 2% or more. The sensitivity and specificity were 77.8% and 65.0%, respectively. These results were presented at RSNA 2017.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (2 results)

All 2017 2016

All Presentation (2 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] Amide proton transfer (APT) imaging of parotid tumors: differentiation between malignant and benign tumors2017

    • Author(s)
      Takeshi Kamitani, Satoshi Kawanami, Koji Sagiyama, Osamu Togao, Yuzo Yamasaki, Hiroshi Honda, Takuya Hino, Ryuji Yasumatsu, Hidetake Yabuuchi
    • Organizer
      103rd Scientific Assembly and Annual Meeting of Radiological Society of North America
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] MR Imaging of Parotid Gland Tumors: Added Value of Permeability MR Imaging2016

    • Author(s)
      H Yabuuchi, MD, Fukuoka, Fukuoka JAPAN; S Kawanami, MD; T Kamitani, MD; K Sagiyama, MD; Y Yamasaki, MD; H Honda, MD; et al.
    • Organizer
      RSNA2016
    • Place of Presentation
      シカゴ
    • Year and Date
      2016-11-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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