| Project/Area Number |
15K09935
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Iwate Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
和田 司 岩手医科大学, 医学部, 准教授 (00275570)
別府 高明 岩手医科大学, 医学部, 教授 (70275543)
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| Co-Investigator(Renkei-kenkyūsha) |
Ogasawara Kuniaki 岩手医科大学, 医学部, 教授 (00305989)
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| Research Collaborator |
Yoshioka Yoshichika
Mori Yuki
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | MRI / 拡散強調 / DWI / intravoxel incoherent / 虚血 / chronic ischemia / diffusion / IVIM / rat / common carotid artery / occlusion / moyamoya disease / 脳虚血 |
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| Outline of Final Research Achievements |
In the present study, we investigated about development of new radiographic diagnosis technique based on diffusion-weighted imaging (DWI) at ultra-high field magnetic resonance (MR) imaging system. In animal experiments, intravoxel incoherent motion (IVIM) based on DWI can non-invasively assess abnormal cerebral hemodynamic states in severe ischemic rats. We will apply the analytical technique for human research using clinical 7 Tesla MR scanner.
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