Developement of new non-invasive method based on diffusion-weighted imaging for the radiographic diagnosis
Project/Area Number |
15K09935
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Radiation science
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Research Institution | Iwate Medical University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
和田 司 岩手医科大学, 医学部, 准教授 (00275570)
別府 高明 岩手医科大学, 医学部, 教授 (70275543)
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Co-Investigator(Renkei-kenkyūsha) |
Ogasawara Kuniaki 岩手医科大学, 医学部, 教授 (00305989)
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Research Collaborator |
Yoshioka Yoshichika
Mori Yuki
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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Keywords | MRI / 拡散強調 / DWI / intravoxel incoherent / 虚血 / chronic ischemia / diffusion / IVIM / rat / common carotid artery / occlusion / moyamoya disease / 脳虚血 |
Outline of Final Research Achievements |
In the present study, we investigated about development of new radiographic diagnosis technique based on diffusion-weighted imaging (DWI) at ultra-high field magnetic resonance (MR) imaging system. In animal experiments, intravoxel incoherent motion (IVIM) based on DWI can non-invasively assess abnormal cerebral hemodynamic states in severe ischemic rats. We will apply the analytical technique for human research using clinical 7 Tesla MR scanner.
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Report
(4 results)
Research Products
(31 results)
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[Journal Article] Preoperative prediction of cerebral hyperperfusion after carotid endarterectomy using middle cerebral artery signal intensity in 1.5-tesla magnetic resonance angiography followed by cerebrovascular reactivity to acetazolamide using brain perfusion single-photon emission computed tomography2016
Author(s)
Yoshida J, Ogasawara K, Chida K, Oikawa K, Matsumoto Y, Nomura JI, Ogasawara Y, Fujiwara S, Kobayashi M, Yoshida K, Terasaki K, Ogawa A
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Journal Title
Neurol Res
Volume: -
Pages: -
Related Report
Peer Reviewed
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[Presentation] Feasibility of 1H-MRS brain temperature map to detect hemodynamic abnormality in patients with unilateral chronic major cerebral artery steno-occlusive disease2017
Author(s)
Namba T, Ogasawara K, Nishimoto H, Ishigaki D, Yoshioka Y, Murakami T, Sasaki M, Kobayashi M, Yoshida K, Uwano I, Fujiwara S, Terasaki K, and Ogawa A
Organizer
ISMRM 25th Annual Meeting and Exhibition 2017
Related Report
Int'l Joint Research
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[Presentation] Relationship between the position of the plaque signal intensity identified by 3D-FSE T1W MR plaque imaging and development of microembolic signals on transcranial Doppler during exposure procedure of carotid arteries in endarterectomy2016
Author(s)
Ogasawara Y, Ogasawara K, Sato Y, Narumi S, Sasaki M, Kobayashi M, Fujiwara S, Yoshida K, Terayama Y, Ogawa A
Organizer
ISMRM 24th Annual Meeting and Exhibition 2016
Place of Presentation
Suntec Singapore Convention & Exhibition Centre, Singapore
Year and Date
2016-05-07 – 2016-05-13
Related Report
Int'l Joint Research
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[Presentation] Assessment of brain temperature and white matter damage in subacute carbon monoxide poisoned patients using diffusion tensor imaging2015
Author(s)
Fujiwara S, Yoshioka Y, Matsuda T, Nishimoto H, Murakami T, Ogawa A, Ogasawara K, Beppu T
Organizer
European Society of Neuroradiology, 38th Annual Meeting
Place of Presentation
Hotel Royal Continental, Naples, Italy
Year and Date
2015-09-17 – 2015-09-20
Related Report
Int'l Joint Research
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[Presentation] Relationship between brain temperature and white matter damage in subacute carbon monoxide poisoned patients2015
Author(s)
Fujiwara S, Yoshioka Y, Matsuda T, Nishimoto H, Murakami T, Nanba T, Ogawa A, Ogasawara K, Beppu T
Organizer
European Academy of Neurology,1st Congress
Place of Presentation
Messe Berlin, Berlin, Germany
Year and Date
2015-06-20 – 2015-06-23
Related Report
Int'l Joint Research
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[Presentation] Diffusion-weighted thermometry using subarachnoid space cerebrospinal fluid in subacute carbon monoxide poisoning patients2015
Author(s)
Fujiwara S, Yoshioka Y, Matsuda T, Nishimoto H, Murakami T, Ogawa A, Ogasawara K, Sasaki M, Beppu T
Organizer
International Society for Magnetic Resonance in Medicine, 23rd Annual Meeting and Exhibition 2015
Place of Presentation
Metro Tronto Convention Center, Toronto, Canada
Year and Date
2015-05-30 – 2015-06-05
Related Report
Int'l Joint Research
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