| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Outline of Final Research Achievements |
Hyperthermia using magnetic nanoparticles and alternating magnetic field has been investigated in the past two decades and is promising for cancer therapy. However, in most cases, magnetic nanoparticles are simply administered by direct injection into the tumor, and the modality just treats only a few space-occupying lesions so far. We hypothesized that if the MNPs were delivered cancer specifically at the cellular level, Hyperthermia using magnetic nanoparticles would have the potential to treat various sorts of disseminated cancer diseases. The aim of this study was to seek for the cancer specific delivery system of immuno- magnetic nanoparticles and to establish the cancer selective intracellular hyperthermia.
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