Development of dosimetric verification system for four-dimensional radiotherapy

• Project/Area Number: 15K09995
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Osaka University
• Principal Investigator: SUMIDA IORI 大阪大学, 医学系研究科, 助教 (10425431)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 動体ファントム / 線量検証 / シンチレーター / QA / 4次元線量検証 / 動体追尾 / 放射線治療 / 線量分布 / 4次元

Outline of Final Research Achievements

We developed the dose verification system using plastic scintilator and optical fiber, that can measure the point absolute dose in Gy without perturbation of the detector in the measurement condition. Second, the motion phantom utilizing four motion axes, which are able to be controled by four servo motors, was developed. After the tracking accuracy of the CyberKnife machine was evaluated and then the dosimetric accuracy of the CyberKnife during motion tracking was evaluated using the developed system. It was found that the overall accuracy in dose between calculated and measured was less than 3%.

Research Products

• [Journal Article] Dosimetric impact of intra-fraction prostate motion under a tumour-tracking system in hypofractionated robotic radiosurgery. (2018)
  • Author(s): Koike Y, Sumida I, Mizuno H, Shiomi H, Kurosu K, Ota S, Yoshioka Y, Suzuki O, Tamari K, Ogawa K.
  • Journal Title: PLoS One. Volume: 13 Issue: 4 Pages: e0195296-e0195296
  • DOI: 10.1371/journal.pone.0195296
  • Peer Reviewed / Open Access
• [Journal Article] Dosimetric and clinical effects of interfraction and intrafraction correlation errors during marker-based real-time tumor tracking for liver SBRT (2017)
  • Author(s): Kurosu Keita、Sumida Iori、Suzuki Osamu、Shiomi Hiroya、Ota Seiichi、Otani Keisuke、Tamari Keisuke、Seo Yuji、Ogawa Kazuhiko
  • Journal Title: Journal of Radiation Research Volume: 59 Issue: 2 Pages: 164-172
  • DOI: 10.1093/jrr/rrx067
  • Peer Reviewed / Open Access
• [Journal Article] Robust measurement point for dose verification in delivery quality assurance for robotic radiosurgery system (2016)
  • Author(s): K. Kurosu, I. Sumida, H. Shiomi, H. Mizuno, H. Yamaguchi, H. Okubo, K. Tamari, Y. Seo, O. Suzuki, S. Ota, S. Inoue, and K. Ogawa
  • Journal Title: J. Radiat. Res（印刷中） Volume: － Issue: 3 Pages: 378-385
  • DOI: 10.1093/jrr/rrw103
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Evaluation of tracking accuracy of the CyberKnife system using a webcam and printed calibrated grid (2016)
  • Author(s): Iori Sumida, Hiroya Shiomi, Naokazu Higashinaka, Yoshikazu Murashima, Youichi Miyamoto, Hideya Yamazaki, Nobuhisa Mabuchi, Eimei Tsuda, and Kazuhiko Ogawa
  • Journal Title: JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS Volume: 17 Issue: 2 Pages: 74-84
  • DOI: 10.1120/jacmp.v17i2.5914
  • Peer Reviewed / Open Access / Int'l Joint Research