| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The gastrointestinal stromal tumor (GIST) arising under the mucosa has difficulty in clinical diagnosis unlike the diagnosis of the cancer. Aim of the research is to develope the new assay that can identify the specific DNA mutant of GIST in the mixed sample of tumor and normal cells.
After various condition tests by basic experiment, we developed high sensitivity assay that became able to identify specific mutation.
The assay was finally applied to to a very small amount of samples obtained from the clinical specimen, and the specific DNA mutation in the gene of GIST was successfully detected by the assay.
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