The development of detection of cancer cells with gGlu-HMRG and clinical application
| Project/Area Number |
15K10056
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General surgery
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| Research Institution | Kagoshima University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
三森 功士 九州大学, 大学病院, 教授 (50322748)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 癌細胞可視化 |
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| Outline of Final Research Achievements |
1) Improvement of condition for clinical application; The detection sensitivity of existing equipment is low, and it turned out that there is a limit to the amount of specimen that can be measured at one time. We undertook a business tie-up, and aimed ① improvement of the optical system, ② reconsideration the equipment design for measuring a large number of specimens at the same time ③ developing software which can judge and display the fluorescence positive area. Currently we are accumulating cases and developing equipment.
2) Discovering the genetic mechanism of GGT expression; Samples which are necessary for analysis have not been obtained due to 1). We are studying the relationship between the expression of GGT protein and the effect of cancer radiotherapy and the expression with protein related to oxidative stress.
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Report
(4 results)
Research Products
(3 results)
