Subcallosal and Heubner artery infarcts following surgical repair of an anterior communicating artery aneurysm
| Project/Area Number |
15K10290
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurosurgery
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
藤村 幹 東北大学, 医学系研究科, 非常勤講師 (00361098)
麦倉 俊司 東北大学, 大学病院, 准教授 (20375017)
森 悦朗 東北大学, 医学系研究科, 名誉教授 (30368477)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | くも膜下出血 / 脳動脈瘤 / 認知機能障害 / 記憶 / MRI / 健忘症 / 動脈瘤 / 記憶障害 / 高次脳機能障害 / 前交通動脈瘤 |
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| Outline of Final Research Achievements |
Postoperative infarctions following surgical repair of anterior communicating artery (ACoA) aneurysms are classified as involvement of the subcallosal artery (the largest unpaired perforator of the ACoA), the recurrent artery of Heubner (RAH), or a combination of both. Postoperative amnesia is most likely caused by an infarction in the territory of the subcallosal artery, particularly in the column of the fornix, a constituent of the Papez neuronal circuit. Infarction in the RAH territory alone is unlikely to cause significant amnesia. Infarcted foci in the RAH territory, when associated with a subcallosal artery infarction, can cause considerable frontal dysfunction due to impaired frontostriatal circuits in patients with postoperative amnesia, with resultant worsening of the long-term outcome or quality of life.
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Report
(4 results)
Research Products
(30 results)
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[Journal Article] Quantitative Analysis of Contrast-Enhanced Ultrasound Imaging in Invasive Breast Cancer: A Novel Technique to Obtain Histopathologic Information of Microvessel Density.2017
Author(s)
Mori N, Mugikura S, Takahashi S, Ito K, Takasawa C, Li L, Miyashita M, ko Kasajima A, Mori Y, Ishida T, Kodama T, Takase K
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Journal Title
Ultrasound in Medicine & Biology
Volume: 43(3)
Pages: 607-614
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Gender differences in ventromedial prefrontal cortex activity associated with valuation of faces2016
Author(s)
Ito A, Fujii T, Abe N, Kawasaki I, Hayashi A, Ueno A, Yoshida K, Sakai S, Mugikura S, Takahashi S, Mori E.
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Journal Title
Neuroscience
Volume: 328
Pages: 194-200
DOI
Related Report
Peer Reviewed
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[Journal Article] Peritumoral apparent diffusion coefficients for prediction of lymphovascular invasion in clinically node-negative invasive breast cancer2016
Author(s)
Mori N, Mugikura S, Takasawa C, Miyashita M, Shimauchi A, Ota H, Ishida T, Kasajima A, Takase K, Kodama T, Takahashi S.
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Journal Title
Eur Radiol
Volume: 26(2)
Pages: 331-339
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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