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Shear stiffness of intracranial tumors using MRE

Research Project

Project/Area Number 15K10359
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurosurgery
Research InstitutionHamamatsu University School of Medicine

Principal Investigator

Sakai Naoto  浜松医科大学, 医学部附属病院, 特任研究員 (20550172)

Co-Investigator(Kenkyū-buntansha) 竹原 康雄  名古屋大学, 医学系研究科, 寄附講座教授 (70188217)
Co-Investigator(Renkei-kenkyūsha) 山下 修平  浜松医科大学, 医学部附属病院, 講師 (90402312)
馬場 聡  浜松医科大学, 医学部附属病院, 准教授 (10242760)
難波 宏樹  浜松医科大学, 医学部附属病院, 教授 (60198405)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords脳腫瘍 / 頭蓋内腫瘍 / 硬さ / 弾性率 / MRI / MRE / エラストグラフィー / 脳神経外科 / MR Elastography / intracranial tumors / stiffness / consisitency / meningioma / pituitary adenoma / vestibular schwannoma / glioma / shear stiffness / tumor consistency / meningiomas / pituitary adenomas / vestibular shwannoma / gliomas
Outline of Final Research Achievements

The degree of tumor stiffness or consisitency is critical information for precise neurosurgical resection of intracranial tumors. MR eastography(MRE) is an emarging technology enabling the noninvasive assessment of the viscoelastic properties of tissues in vitro.We evaluated the stiffness of 4 common intracranial tumors:meningiomas,pituitary adenomas,vestibular schwannoma and gliomas using MRE and tested whether MRE had the potential to discriminate firm tumors preoperatively.As the result, MRE could evaluate those intracranial tumors on the basis of their physical property of shear stiffness. MRE may be useful in the preoperative discrimination of firm tumors.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (5 results)

All 2016 2015

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (4 results)

  • [Journal Article] Shear Stiffness of 4 Common Intracranial Tumors Measured Using MR Elastography: Comparison with Intraoperative Consistency Grading2016

    • Author(s)
      N.Sakai, Y.Takehara, S. Yamashita、N. Ohishi, H. Kawaji, T. Sameshima, S. Baba, H. Sakahara, H. Namba
    • Journal Title

      AJNR Am J Neuroradiol

      Volume: 37 Pages: 1851-1859

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] MRエラストグラフィーによる下垂体腺腫の弾性率の評価2016

    • Author(s)
      酒井直人
    • Organizer
      第26回日本間脳下垂体腫瘍学会
    • Place of Presentation
      ザ・セレクトイン福島
    • Year and Date
      2016-02-19
    • Related Report
      2015 Research-status Report
  • [Presentation] 核磁気共鳴エラストグラフィー(MRE)は硬い頭蓋内腫瘍を術前に鑑別できる2016

    • Author(s)
      酒井直人
    • Organizer
      第39回日本脳神経CI学会総会
    • Place of Presentation
      日経ホール&カンファレンスルーム
    • Year and Date
      2016-01-29
    • Related Report
      2015 Research-status Report
  • [Presentation] 核磁気共鳴エラストグラフィーによる良性頭蓋内腫瘍のずり弾性率の術前評価2015

    • Author(s)
      酒井直人
    • Organizer
      第20回日本脳腫瘍の外科学会
    • Place of Presentation
      名古屋観光ホテル
    • Year and Date
      2015-09-25
    • Related Report
      2015 Research-status Report
  • [Presentation] Magnetic resonance elastography(MRE)による頭蓋内腫瘍のずり弾性率の術前評価の有用性2015

    • Author(s)
      酒井直人
    • Organizer
      第27回日本頭蓋底外科学会
    • Place of Presentation
      名古屋国際会場
    • Year and Date
      2015-07-09
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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