| Project/Area Number |
15K10359
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neurosurgery
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| Research Institution | Hamamatsu University School of Medicine |
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Principal Investigator |
Sakai Naoto 浜松医科大学, 医学部附属病院, 特任研究員 (20550172)
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| Co-Investigator(Kenkyū-buntansha) |
竹原 康雄 名古屋大学, 医学系研究科, 寄附講座教授 (70188217)
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| Co-Investigator(Renkei-kenkyūsha) |
山下 修平 浜松医科大学, 医学部附属病院, 講師 (90402312)
馬場 聡 浜松医科大学, 医学部附属病院, 准教授 (10242760)
難波 宏樹 浜松医科大学, 医学部附属病院, 教授 (60198405)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 脳腫瘍 / 頭蓋内腫瘍 / 硬さ / 弾性率 / MRI / MRE / エラストグラフィー / 脳神経外科 / MR Elastography / intracranial tumors / stiffness / consisitency / meningioma / pituitary adenoma / vestibular schwannoma / glioma / shear stiffness / tumor consistency / meningiomas / pituitary adenomas / vestibular shwannoma / gliomas |
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| Outline of Final Research Achievements |
The degree of tumor stiffness or consisitency is critical information for precise neurosurgical resection of intracranial tumors. MR eastography(MRE) is an emarging technology enabling the noninvasive assessment of the viscoelastic properties of tissues in vitro.We evaluated the stiffness of 4 common intracranial tumors:meningiomas,pituitary adenomas,vestibular schwannoma and gliomas using MRE and tested whether MRE had the potential to discriminate firm tumors preoperatively.As the result, MRE could evaluate those intracranial tumors on the basis of their physical property of shear stiffness. MRE may be useful in the preoperative discrimination of firm tumors.
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