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The relationship between the pedicle screw size and biomechanical stability of screw placed in the spine

Research Project

Project/Area Number 15K10409
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionKyushu University

Principal Investigator

HARIMAYA Katsumi  九州大学, 大学病院, 准教授 (40335972)

Co-Investigator(Kenkyū-buntansha) 久保田 健介  独立行政法人労働者健康安全機構総合せき損センター(研究部), 独立行政法人労働者健康安全機構総合せき損センター(研究部), 研究員(移行) (00717069)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords椎弓根スクリュー / 椎弓根拡大率 / 力学的強度
Outline of Final Research Achievements

Pedicle screw-based instrumentation is one of the most popular implants in spinal fixation. However, there are few reports regarding the appropriate screw size which maintains the biomechanical strength in the pedicle. In this study, we examined the relationship between the pedicle screw size and biomechanical stability of screw placed in the immature and mature spine. Micro CT scans of the pedicles were taken after every tapping operation and radiological findings of pedicle were examined. The pedicle screws (6.5 - 11.5 mm) were tested using pullout testing with tensile tester. In mature vertebrae, the largest diameter of the screw that did not cause pedicle failure was 10.8 ± 1.2 mm, which was 117 ± 19 % of their original pedicle diameter. Immature pedicles were more expanded by application of serial tappings without osseous branch than mature pedicles (125 ± 14 % of their original diameter). The pullout strength of the screw was maintained as long as bony branch was not observed.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (12 results)

All 2018 2017 2016 2015

All Journal Article (9 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 9 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (3 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] A Replication Study for the Association of rs11190870 With Curve Severity in Adolescent Idiopathic Scoliosis in Japanese2018

    • Author(s)
      Takahashi Yohei、Kou Ikuyo、Ogura Yoji、Miyake Atsushi、Takeda Kazuki、Nakajima Masahiro、Minami Shohei、Kawakami Noriaki、Uno Koki、Ito Manabu、Chiba Kazuhiro et al.
    • Journal Title

      SPINE

      Volume: 43 Issue: 10 Pages: 688-692

    • DOI

      10.1097/brs.0000000000002413

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Experimental Mouse Model of Lumbar Ligamentum Flavum Hypertrophy.2017

    • Author(s)
      Saito T, Yokota K, Kobayakawa K, Hara M, Kubota K, Harimaya K, Kawaguchi K, Hayashida M, Matsumoto Y, Doi T, Shiba K, Nakashima Y, Okada S.
    • Journal Title

      PLoS One

      Volume: 6 Issue: 1 Pages: 1-15

    • DOI

      10.1371/journal.pone.0169717

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Claudin 6 expression is useful to distinguish myxofibrosarcomas from other myxoid soft tissue tumors2017

    • Author(s)
      Bekki Hirofumi、Yamamoto Hidetaka、Takizawa Katsumi、Iwasaki Takeshi、Otsuka Hiroshi、Yamada Yuichi、Kohashi Kenichi、Harimaya Katsumi、Iwamoto Yukihide、Oda Yoshinao
    • Journal Title

      Pathology - Research and Practice

      Volume: 213 Issue: 6 Pages: 674-679

    • DOI

      10.1016/j.prp.2016.12.001

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Does Modic Change Progresss With Age?2017

    • Author(s)
      Tarukado Kiyoshi、Ono Teruaki、Tono Osamu、Tanaka Hiroki、Ikuta Ko、Harimaya Katsumi、Doi Toshio
    • Journal Title

      SPINE

      Volume: 42 Issue: 23 Pages: 1805-1809

    • DOI

      10.1097/brs.0000000000002254

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin?N-cadherin pathway after spinal cord injury2017

    • Author(s)
      Hara Masamitsu、Kobayakawa Kazu、Ohkawa Yasuyuki、Kumamaru Hiromi、Yokota Kazuya、Saito Takeyuki、Kijima Ken、Yoshizaki Shingo、Harimaya Katsumi、Nakashima Yasuharu、Okada Seiji
    • Journal Title

      Nature Medicine

      Volume: 23 Issue: 7 Pages: 818-828

    • DOI

      10.1038/nm.4354

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Does an osteoporotic vertebral fracture treated by balloon kyphoplasty successfully achieve bone union during the follow-up? A retrospective study with a minimum 2-year follow-up2017

    • Author(s)
      Tarukado Kiyoshi、Tono Osamu、Harimaya Katsumi、Doi Toshio
    • Journal Title

      Journal of Orthopaedics

      Volume: 14 Issue: 4 Pages: 480-483

    • DOI

      10.1016/j.jor.2017.08.005

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Macrophage Infiltration Is a Causative Factor for Ligamentum Flavum Hypertrophy through the Activation of Collagen Production in Fibroblasts2017

    • Author(s)
      Saito Takeyuki、Hara Masamitsu、Kumamaru Hiromi、Kobayakawa Kazu、Yokota Kazuya、Kijima Ken、Yoshizaki Shingo、Harimaya Katsumi、Matsumoto Yoshihiro、Kawaguchi Kenichi、Hayashida Mitsumasa、Inagaki Yutaka、Shiba Keiichiro、Nakashima Yasuharu、Okada Seiji
    • Journal Title

      The American Journal of Pathology

      Volume: 187 Issue: 12 Pages: 2831-2840

    • DOI

      10.1016/j.ajpath.2017.08.020

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A functional variant in MIR4300HG, the host gene of microRNA MIR4300 is associated with progression of adolescent idiopathic scoliosis2017

    • Author(s)
      Ogura Yoji、Kou Ikuyo、Takahashi Yohei、Takeda Kazuki、Minami Shohei、Kawakami Noriaki、Uno Koki、Ito Manabu、Yonezawa Ikuho、Kaito Takashi、Yanagida Haruhisa、Watanabe Kei、Taneichi Hiroshi、Harimaya Katsumi、Taniguchi Yuki、Kotani Toshiaki、Chiba Kazuhiro、et a.
    • Journal Title

      Human Molecular Genetics

      Volume: 26 Issue: 20 Pages: 4086-4092

    • DOI

      10.1093/hmg/ddx291

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cancer-testis antigen expression in synovial sarcoma: NY-ESO-1, PRAME, MAGEA4, and MAGEA1.2016

    • Author(s)
      Iura K, Maekawa A, Kohashi K, Ishii T, Bekki H, Otsuka H, Yamada Y, Yamamoto H, Harimaya K, Iwamoto Y, Oda Y.
    • Journal Title

      Hum Pathol

      Volume: Mar;61 Pages: 130-139

    • DOI

      10.1016/j.humpath.2016.12.006

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] Pedicle screw挿入に伴う椎弓根拡大率と力学的強度の関係2016

    • Author(s)
      久保田健介 播广谷勝三 岡田誠司 前田健  高尾恒彰  芝啓一郎
    • Organizer
      第46回日本側彎症学会
    • Place of Presentation
      京都
    • Year and Date
      2016-11-17
    • Related Report
      2016 Research-status Report
  • [Presentation] The Influence of Increasing Pedicle Screw Size on the Pullout Force of Pedicle Screws : Comparison between Immature and Mature Porcine Spine2016

    • Author(s)
      Kensuke Kubota, Katsumi Harimaya, Seiji Okada, Kazu Kobayakawa, Masamitsu Hara, Yukihide Iwamoto
    • Organizer
      Orthopaedic Research Society (ORS) 2016 Annual Meeting
    • Place of Presentation
      Orlando, Florida, USA
    • Year and Date
      2016-03-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] The Relationship Between The Diameter Of Pedicle Screw And The Biomechanical Strength Of Screws Placed In The Immature Porcine Spine2015

    • Author(s)
      Kensuke Kubota, Katsumi Harimaya, Seiji Okada, Mitsumasa Hayashida, Yoshihiro Matsumoto, Yukihide Iwamoto
    • Organizer
      the 16th European Federation of National Associations of Orthopaedics and Traumatology (EFORT) Congress
    • Place of Presentation
      Prague, Czech Republic
    • Year and Date
      2015-05-27
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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