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Clarification of pathophysiology and prognosis prediction of Refractory peripheral nerve neuropathy using Diffusion tensor MRI

Research Project

Project/Area Number 15K10421
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionTokyo Dental College (2016-2017)
Keio University (2015)

Principal Investigator

Ochi Kensuke  東京歯科大学, 歯学部, 講師 (70445203)

Co-Investigator(Renkei-kenkyūsha) FUJIYOSHI Kanehiro  独立行政法人国立病院機構村山医療センター, 国立病院機構村山医療センター, 医長 (80365303)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords末梢神経 / 画像診断 / 難治性末梢神経障害
Outline of Final Research Achievements

<Clinical research> We have performed diffusion tensor MRI to eight patients (six cubital tunnel syndrome patients, one spontaneous anterior interosseous nerve palsy patient, and one spontaneous posterior interosseous nerve palsy patient). We concluded that interpreting signal changes for peripheral neuropathy that does not have change in the diameter of peripheral nerve is difficult at this point of time.
<Basic research> We have evaluated our peripheral nerve injury model using clip at the Nukada Medical and Biological Research Institute. We have successfully established the injury model with high reproducibility. Although our grant period is over, we will continue our research using diffusion tensor MRI.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (15 results)

All 2018 2017 2016 2015

All Journal Article (8 results) (of which Peer Reviewed: 8 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Invited: 2 results)

  • [Journal Article] A well-differentiated liposarcoma in the digit: A case report of 5-year post-surgical follow-up2018

    • Author(s)
      Mizuno S, Ochi K, Miyauchi T, Watanabe I, Hotta H, Anazawa U
    • Journal Title

      J Hand Surg Asian Pac Vol

      Volume: 印刷中

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Distal Radial Fracture Malunion in Sweden: Is It the Same in Your Region?2018

    • Author(s)
      Ochi, K
    • Journal Title

      J Bone Joint Surg Am

      Volume: 100 Issue: 8 Pages: e52-e52

    • DOI

      10.2106/jbjs.17.01559

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Osteoid Osteoma of the Distal Phalanx of the Ring Finger with Clubbed Finger Deformity: A Case Report2017

    • Author(s)
      Horiuchi, K. Horiuchi, Y. Ochi, K.
    • Journal Title

      J Hand Surg Asian Pac Vol

      Volume: 22 Issue: 02 Pages: 248-250

    • DOI

      10.1142/s0218810417720170

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] High Median nerve palsy caused by pseudoaneurysm after brachial catheterization: Two cases report2017

    • Author(s)
      Ochi K, Iwase G, Mizuno S, Matsumura N, Iwamoto T, Watanabe I, Hotta H, Anazawa U, Sato K, Takayama S.
    • Journal Title

      J Med Cases

      Volume: 8 Issue: 2 Pages: 33-35

    • DOI

      10.14740/jmc2715w

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Association between serum vitamin D level and history of falls in elderly Japanese patients with rheumatoid arthritis.2016

    • Author(s)
      Ochi K, Furuya T, Ikari K, Taniguchi A, Yamanaka H, Momohara S.
    • Journal Title

      Mod Rheumatol.

      Volume: 26 Issue: 3 Pages: 460-462

    • DOI

      10.3109/14397595.2015.1085487

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Modified metacarpal shortening osteotomy of the midcarpal bone for preserving metacarpophalangeal joints in patients with rheumatoid arthritis2016

    • Author(s)
      Ochi K, Sakuma Y, Ishida O, Yano K, Yoshida S, Koyama T, Ishibashi M, Ikari K, Momohara S.
    • Journal Title

      Mod Rheumatol

      Volume: 26 Issue: 2 Pages: 313-314

    • DOI

      10.3109/14397595.2015.1081338

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Interfascicular neurolysis for incomplete spontaneous posterior interosseous nerve palsy with a surgical delay of 17 years: Is it still effective?2015

    • Author(s)
      Ochi K, Horiuchi Y, Arino H, Toyama Y
    • Journal Title

      Hand Surg

      Volume: 20 Issue: 02 Pages: 302-303

    • DOI

      10.1142/s0218810415720089

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Shoulder position increases ulnar nerve strain at the elbow of patients with cubital tunnel syndrome2015

    • Author(s)
      Ochi K, Horiuchi Y, Horiuchi K, Iwamoto T, Morisawa Y, Sato K.
    • Journal Title

      J Shoulder Elbow Surg

      Volume: 24 Issue: 9 Pages: 1380-1385

    • DOI

      10.1016/j.jse.2015.01.014

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] 特発性前骨間神経麻痺と特発性後骨間神経麻痺の前向き多施設臨床研究 (iNPS-JAPAN)調査報告:麻痺発症時の臨床像の分析2018

    • Author(s)
      越智健介、加藤博之、前・後骨間神経麻痺前向き多施設共同研究グループ
    • Organizer
      日本ヒジ関節学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 特発性前骨間神経麻痺および特発性後骨間神経麻痺 ―病態や疫学を中心にー2017

    • Author(s)
      越智健介、加藤博之、堀内行雄、田崎憲一
    • Organizer
      日本手外科学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 特発性前骨間神経麻痺と特発性後骨間神経麻痺の前向き多施設臨床研究 (iNPS-JAPAN)調査報告:麻痺発症時の臨床像の分析2017

    • Author(s)
      越智健介、加藤博之、前・後骨間神経麻痺前向き多施設共同研究グループ
    • Organizer
      日本末梢神経学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 肘部管症候群患者における尺骨神経伸長度―病態との関連―2016

    • Author(s)
      越智健介、堀内行雄、堀内孝一、岩本卓士、佐藤和毅
    • Organizer
      日本手外科学会学術集会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2016-04-21
    • Related Report
      2015 Research-status Report
  • [Presentation] 特発性前骨間神経麻痺と特発性後骨間神経麻痺の前向き多施設臨床研究 (iNPS-JAPAN)における術中所見: 第3報2016

    • Author(s)
      越智健介、加藤博之、前・後骨間神経麻痺前向き多施設共同研究グループ
    • Organizer
      日本肘関節学会学術集会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Year and Date
      2016-02-11
    • Related Report
      2015 Research-status Report
  • [Presentation] 特発性前骨間神経麻痺と特発性後骨間神経麻痺の前向き多施設臨床研究 (iNPS-JAPAN)調査報告2015

    • Author(s)
      越智健介、加藤博之、前・後骨間神経麻痺前向き多施設共同研究グループ
    • Organizer
      日本末梢神経学会学術集会
    • Place of Presentation
      ホテルブエナビスタ(長野県松本市)
    • Year and Date
      2015-09-18
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 肘部管症候群患者における尺骨神経伸長度と肩関節内旋外転の関係2015

    • Author(s)
      越智健介、堀内行雄、森田晃造、堀内孝一、大橋麻依子、ほか
    • Organizer
      日本整形外科学会総会
    • Place of Presentation
      神戸コンベンションセンター(兵庫県神戸市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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