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Analysisi of the patient matched spinal alignment based on the patient demographics

Research Project

Project/Area Number 15K10424
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Orthopaedic surgery
Research InstitutionKeio University (2016-2017)
National Hospital Organization Murayama Medical Center (2015)

Principal Investigator

YAGI MITSURU  慶應義塾大学, 医学部(信濃町), 講師 (40338091)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords脊椎 / アライメント / 骨密度 / 側弯 / 後弯 / 成人脊柱変形 / 矯正固定術 / バイオメカニクス / バランス
Outline of Final Research Achievements

The relationship between gait pattern, spinal alignment and the level of upper instrumented vertebra (UIV) in surgically treated patients with adult spinal deformity (ASD) has not been fully documented. Our study aimed to assess the effect of UIV level for the gait pattern and spinal alignment in ASD. Both UT and LT groups achieved similar improvement of gait ability and pattern after surgery. Additional studies will be needed to further define the effect of UIV for the activity of daily living such as fast walking, stepping the stairs, or standing from the chair in ASDs. Additionally, the patients with ASD had an asymmetric gait pattern and impaired gait ability compared with healthy volunteers. Gait ability correlated significantly with the GL, spinopelvic alignment, lower extremity joint ROM, and lean volume. The surgical correction of spinopelvic alignment and exercises to build muscle strength may improve the gait pattern and ability in patients with ASD.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (22 results)

All 2018 2017 2016

All Journal Article (11 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 11 results) Presentation (11 results) (of which Int'l Joint Research: 8 results,  Invited: 5 results)

  • [Journal Article] Low Bone-Mineral Density Is a Significant Risk for Proximal Junctional Failure After Surgical Correction of Adult Spinal Deformity: A Propensity Score-Matched Analysis.2018

    • Author(s)
      Yagi M1,2,3, Fujita N1,3, Tsuji O1,3, Nagoshi N1,3, Asazuma T2, Ishii K3,4, Nakamura M1,3, Matsumoto M1,3, Watanabe K1,3.
    • Journal Title

      Spine (Phila Pa 1976)

      Volume: 1

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of Frailty and Comorbidities on Surgical Outcomes and Complications in Adult Spinal Disorders.2018

    • Author(s)
      Yagi M1,2,3, Fujita N1,3, Okada E1,3, Tsuji O1,3, Nagoshi N1,3, Tsuji T2,3, Asazuma T2, Nakamura M1,3, Matsumoto M1,3, Watanabe K1,3,4.
    • Journal Title

      Spine (Phila Pa 1976)

      Volume: 1 Issue: 18 Pages: 1259-1267

    • DOI

      10.1097/brs.0000000000002596

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of the upper instrumented vertebral level (upper vs. lower thoracic spine) on gait ability after corrective surgery for adult spinal deformity.2018

    • Author(s)
      Yagi M, Fujita N, Tsuji O, Nagoshi N, Yato Y, Asazuma T, Ishii K, Nakamura M, Matsumoto M
    • Journal Title

      Spine J.

      Volume: 1 Issue: 1 Pages: 130-138

    • DOI

      10.1016/j.spinee.2017.06.026

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Does corrective spine surgery improve the standing balance in patients with adult spinal deformity?2018

    • Author(s)
      Yagi M, Fujita N, Tsuji O, Nagoshi N, Yato Y, Asazuma T, Ishii K, Nakamura M, Matsumoto M
    • Journal Title

      Spine J.

      Volume: 1 Issue: 1 Pages: 36-43

    • DOI

      10.1016/j.spinee.2017.05.023

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Replication Study for the Association of rs11190870 With Curve Severity in Adolescent Idiopathic Scoliosis in Japanese2018

    • Author(s)
      Takahashi Yohei、Kou Ikuyo、Ogura Yoji、Miyake Atsushi、Takeda Kazuki、Nakajima Masahiro、Minami Shohei、Kawakami Noriaki、Uno Koki、Ito Manabu、Chiba Kazuhiro et al.
    • Journal Title

      SPINE

      Volume: 43 Issue: 10 Pages: 688-692

    • DOI

      10.1097/brs.0000000000002413

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Walking balance and compensatory gait mechanisms in surgically treated patients with adult spinal deformity.2017

    • Author(s)
      Yagi M, Ohne H, Konomi T, Fujiyoshi K, Kaneko S, Takemitsu M, Machida M, Yato Y, Asazuma T.
    • Journal Title

      Spine J.

      Volume: 3 Issue: 3 Pages: 409-417

    • DOI

      10.1016/j.spinee.2016.10.014

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Role of Ethnicity in Alignment Compensation: Propensity Matched Analysis of Differential Compensatory Mechanism Recruitment Patterns for Sagittal Malalignment in 288 ASD Patients From Japan, Korea, and United States.2017

    • Author(s)
      Diebo BG, Gammal I, Ha Y, Yoon SH, Chang JW, Kim B, Matsumoto M, Yamato Y, Takeuchi D, Hosogane N, Yagi M, Taneichi H, Schwab F, Lafage V, Ames C; International Spine Study Group (ISSG).
    • Journal Title

      Spine

      Volume: 15;42(4) Issue: 4 Pages: E234-E240

    • DOI

      10.1097/brs.0000000000001744

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Drop Body Syndrome -A distinct form of adult spinal deformity.2016

    • Author(s)
      Yagi M, Kaneko S, Yato Y, Asazuma T.
    • Journal Title

      Spine

      Volume: 印刷中 Issue: 16 Pages: 969-977

    • DOI

      10.1097/brs.0000000000002012

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Standing Balance and Compensatory Mechanisms in Patients with Adult Spinal Deformity.2016

    • Author(s)
      Yagi M, Kaneko S, Yato Y, Asazuma T.
    • Journal Title

      Spine

      Volume: 印刷中 Issue: 10 Pages: 584-591

    • DOI

      10.1097/brs.0000000000001901

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Walking sagittal balance correction by pedicle subtraction osteotomy in adults with fixed sagittal imbalance.2016

    • Author(s)
      Yagi M, Kaneko S, Yato Y, Asazuma T, Machida M.
    • Journal Title

      Eur Spine J

      Volume: 25(8) Issue: 8 Pages: 2488-96

    • DOI

      10.1007/s00586-016-4604-3

    • Related Report
      2016 Research-status Report 2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Teriparatide improves volumetric bone mineral density and fine bone structure in the UIV+1 vertebra, and reduces bone failure type PJK after surgery for adult spinal deformity.2016

    • Author(s)
      Yagi M, Ohne H, Konomi T, Fujiyoshi K, Kaneko S, Komiyama T, Takemitsu M, Yato Y, Machida M, Asazuma T.
    • Journal Title

      Osteoporos Int.

      Volume: 24 Issue: 12 Pages: 1-8

    • DOI

      10.1007/s00198-016-3676-6

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] Surgical complication in adult spinal deformity.2016

    • Author(s)
      Yagi M
    • Organizer
      Scoliosis Research Society World Wide Conference.
    • Place of Presentation
      京都国際会議場(京都府京都市)
    • Year and Date
      2016-11-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Teriparatide improves volumetric bone mineral density and fine bone structure in the UIV+1 vertebra, and reduces bone failure type PJK after surgery for adult spinal deformity.2016

    • Author(s)
      Yagi M, Kaneko S, Yato Y, Asazuma T, Machida M.
    • Organizer
      Scoliosis Research Society
    • Place of Presentation
      プラハ
    • Year and Date
      2016-09-21
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Prevention of PJK2016

    • Author(s)
      Yagi M
    • Organizer
      Scoliosis Research Society
    • Place of Presentation
      プラハ
    • Year and Date
      2016-09-21
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Adult scoliosis Prevention strategies of PJK.2016

    • Author(s)
      Yagi M
    • Organizer
      51st Scoliosis Research Society
    • Place of Presentation
      プラハ(チェコ共和国)
    • Year and Date
      2016-09-20
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Teriparatide improves volumetric bone mineral density and fine bone structure in the UIV+1 vertebra, and reduces bone failure type PJK after surgery for adult spinal deformity.2016

    • Author(s)
      Yagi M, Kaneko S, Machida M, Asazuma T.
    • Organizer
      51st Scoliosis Research Society.
    • Place of Presentation
      プラハ(チェコ共和国)
    • Year and Date
      2016-09-20
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Characterization of the standing posture in adult spinal deformity patients.2016

    • Author(s)
      Yagi M, Kaneko S, Yato Y, Machida M, Asazuma T.
    • Organizer
      43rd International Society for Study of Lumbar Spine.
    • Place of Presentation
      シンガポール(シンガポール共和国)
    • Year and Date
      2016-05-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] dult Spinal Deformity, PI-LL mismatch: Indication and Surgery Method for Post Traumatic Kyphosis.2016

    • Author(s)
      Yagi M, Kaneko S, Yato Y, Asazuma T, Matsumoto M
    • Organizer
      The 89th Japan Orthopedic Association Annual meeting international symposium3
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-05-16
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] PI-LL mismatch; post traumatic kyphosis2016

    • Author(s)
      Yagi M, Kaneko S, Asazuma T, Matsumoto M
    • Organizer
      日本整形外科学会国際シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2016-05-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 成人脊柱変形患者の立位バランスの評価 ー冠状面バランスの不良は矢状面バランスに影響を与えるー2016

    • Author(s)
      八木満、金子慎二郎、谷戸祥之、朝妻孝仁
    • Organizer
      日本脊椎脊髄病学会シンポジウム
    • Place of Presentation
      福岡
    • Year and Date
      2016-04-14
    • Related Report
      2015 Research-status Report
  • [Presentation] 脊椎矯正固定術は成人脊柱変形患者の歩行能力を改善するか?2016

    • Author(s)
      八木満、金子慎二郎、谷戸祥之、朝妻孝仁
    • Organizer
      日本脊椎脊髄病学会
    • Place of Presentation
      福岡
    • Year and Date
      2016-04-14
    • Related Report
      2015 Research-status Report
  • [Presentation] 脊椎矯正固定術は成人脊柱変形患者の立位バランスを改善するか?2016

    • Author(s)
      八木満、金子慎二郎、谷戸祥之、朝妻孝仁
    • Organizer
      日本脊椎脊髄病学会
    • Place of Presentation
      福岡
    • Year and Date
      2016-04-14
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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