Analysisi of the patient matched spinal alignment based on the patient demographics
Project/Area Number |
15K10424
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Orthopaedic surgery
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Research Institution | Keio University (2016-2017) National Hospital Organization Murayama Medical Center (2015) |
Principal Investigator |
YAGI MITSURU 慶應義塾大学, 医学部(信濃町), 講師 (40338091)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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Keywords | 脊椎 / アライメント / 骨密度 / 側弯 / 後弯 / 成人脊柱変形 / 矯正固定術 / バイオメカニクス / バランス |
Outline of Final Research Achievements |
The relationship between gait pattern, spinal alignment and the level of upper instrumented vertebra (UIV) in surgically treated patients with adult spinal deformity (ASD) has not been fully documented. Our study aimed to assess the effect of UIV level for the gait pattern and spinal alignment in ASD. Both UT and LT groups achieved similar improvement of gait ability and pattern after surgery. Additional studies will be needed to further define the effect of UIV for the activity of daily living such as fast walking, stepping the stairs, or standing from the chair in ASDs. Additionally, the patients with ASD had an asymmetric gait pattern and impaired gait ability compared with healthy volunteers. Gait ability correlated significantly with the GL, spinopelvic alignment, lower extremity joint ROM, and lean volume. The surgical correction of spinopelvic alignment and exercises to build muscle strength may improve the gait pattern and ability in patients with ASD.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] Low Bone-Mineral Density Is a Significant Risk for Proximal Junctional Failure After Surgical Correction of Adult Spinal Deformity: A Propensity Score-Matched Analysis.2018
Author(s)
Yagi M1,2,3, Fujita N1,3, Tsuji O1,3, Nagoshi N1,3, Asazuma T2, Ishii K3,4, Nakamura M1,3, Matsumoto M1,3, Watanabe K1,3.
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Journal Title
Spine (Phila Pa 1976)
Volume: 1
Related Report
Peer Reviewed
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[Journal Article] Impact of Frailty and Comorbidities on Surgical Outcomes and Complications in Adult Spinal Disorders.2018
Author(s)
Yagi M1,2,3, Fujita N1,3, Okada E1,3, Tsuji O1,3, Nagoshi N1,3, Tsuji T2,3, Asazuma T2, Nakamura M1,3, Matsumoto M1,3, Watanabe K1,3,4.
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Journal Title
Spine (Phila Pa 1976)
Volume: 1
Issue: 18
Pages: 1259-1267
DOI
Related Report
Peer Reviewed
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[Journal Article] Role of Ethnicity in Alignment Compensation: Propensity Matched Analysis of Differential Compensatory Mechanism Recruitment Patterns for Sagittal Malalignment in 288 ASD Patients From Japan, Korea, and United States.2017
Author(s)
Diebo BG, Gammal I, Ha Y, Yoon SH, Chang JW, Kim B, Matsumoto M, Yamato Y, Takeuchi D, Hosogane N, Yagi M, Taneichi H, Schwab F, Lafage V, Ames C; International Spine Study Group (ISSG).
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Journal Title
Spine
Volume: 15;42(4)
Issue: 4
Pages: E234-E240
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Teriparatide improves volumetric bone mineral density and fine bone structure in the UIV+1 vertebra, and reduces bone failure type PJK after surgery for adult spinal deformity.2016
Author(s)
Yagi M, Ohne H, Konomi T, Fujiyoshi K, Kaneko S, Komiyama T, Takemitsu M, Yato Y, Machida M, Asazuma T.
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Journal Title
Osteoporos Int.
Volume: 24
Issue: 12
Pages: 1-8
DOI
Related Report
Peer Reviewed
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