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analysis of nystagmus and head position by next generation VOG with high-speed camera and 9-axis sensor

Research Project

Project/Area Number 15K10752
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Otorhinolaryngology
Research InstitutionYamaguchi University

Principal Investigator

HASHIMOTO Makoto  山口大学, 医学部附属病院, 講師 (50343299)

Co-Investigator(Kenkyū-buntansha) 山下 裕司  山口大学, 大学院医学系研究科, 教授 (00210419)
藤井 博則  山口大学, 医学部附属病院, 助教 (50750197)
Project Period (FY) 2015-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsめまい / 平衡医学 / 平衡障害 / video oculography / 眼振
Outline of Final Research Achievements

We have developed video-oculograhy (HI-VOG) using freeware image analysis software ImageJ. HI-VOG requires offline analysis to be performed after recording, manual pupil recognition setting is required. Therefore, we developed an improved real-time three-dimensional analysis video-oculography (VOG). It enables recording and filing, automated pupil recognition and analysis, real-time nystagmus display, detailed analysis, and result report. An infrared flunzel was created using a high-speed camera and an accelerometer. A light weight, high image quality, and high speed are possible. The obtained acceleration and angular velocity are taken into a PC using a small 9-axis sensor device mounted with a 3-axis acceleration sensor, 3-axis angular velocity sensor, and 3-axis geomagnetic sensor, and the head position direction and velocity are analyzed. Analysis was performed in synchronization with the head position information.

Academic Significance and Societal Importance of the Research Achievements

開発した軽量高画質・高速赤外線CCDを用い、日常臨床および臨床研究において、リアルタイムで詳細な眼振、眼球運動を記録することが可能になる。頭位モニタリングセンサは,めまい患者の日常や睡眠頭位の解析など,めまい入院患者の頭位の解析などの研究にも応用できる。頭位,頭位変換眼振検査および頭位治療にブレークスルーをもたらすと考える。

Report

(5 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Research-status Report
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (31 results)

All 2019 2018 2017 2016 2015

All Journal Article (8 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (22 results) (of which Int'l Joint Research: 7 results,  Invited: 3 results) Book (1 results)

  • [Journal Article] Quantitative Analysis of Smooth Pursuit Eye Movement Using Video-Oculography2018

    • Author(s)
      Hironori Fujii, Makoto Hashimoto, Kazuma Sugahara, Takuo Ikeda, Yoshinobu Hirose, Hiroshi Yamashita
    • Journal Title

      Archives of Otolaryngology and Rhinology

      Volume: - Pages: 030-034

    • DOI

      10.17352/2455-1759.000071

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 【耳の検査のコツとピットフォール】 聴覚検査 語音聴力検査2018

    • Author(s)
      橋本 誠、山下裕司
    • Journal Title

      JOHNS

      Volume: 34 Pages: 827-831

    • Related Report
      2018 Annual Research Report
  • [Journal Article] Protective effect of an astaxanthin nanoemulsion against neomycin-induced hair-cell damage in zebrafish2018

    • Author(s)
      Takemoto Yosuke、Hirose Yoshinobu、Sugahara Kazuma、Hashimoto Makoto、Hara Hirotaka、Yamashita Hiroshi
    • Journal Title

      Auris Nasus Larynx

      Volume: 45 Issue: 1 Pages: 20-25

    • DOI

      10.1016/j.anl.2017.02.001

    • Related Report
      2017 Research-status Report 2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Oral administration of geranylgeranylacetone to protect vestibular hair cells2018

    • Author(s)
      Nagato Shinpei、Sugahara Kazuma、Hirose Yoshinobu、Takemoto Yousuke、Hashimoto Makoto、Fujii Hironori、Yamashita Hiroshi
    • Journal Title

      Auris Nasus Larynx

      Volume: 45 Issue: 3 Pages: 412-416

    • DOI

      10.1016/j.anl.2017.07.006

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 【もう迷わない耳鼻咽喉科疾患に対する向精神薬の使い方】 向精神薬の使い方 前庭神経炎に対する向精神薬の適応と使い方2017

    • Author(s)
      橋本 誠、 山下裕司
    • Journal Title

      ENTONI

      Volume: 210 Pages: 68-71

    • Related Report
      2017 Research-status Report
  • [Journal Article] Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea.2016

    • Author(s)
      Yoshinobu Hirose, Kazuma Sugahara, Eiju Kanagawa, Yousuke Takemoto, Makoto Hashimoto, Hiroshi Yamashita.
    • Journal Title

      Hearing Research.

      Volume: 342 Pages: 80-85

    • DOI

      10.1016/j.heares.2016.10.001

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] ナノ製剤による側線器有毛細胞保護効果の検討ーゼブラフィッシュを用いてー2016

    • Author(s)
      竹本洋介, 広瀬敬信, 菅原一真, 橋本 誠, 藤井博則, 山下裕司.
    • Journal Title

      耳鼻咽喉科ニューロサイエンス

      Volume: 30 Pages: 32-34

    • Related Report
      2016 Research-status Report
  • [Journal Article] めまい症状尺度短縮版(Vertigo Symptom Scale-short form)日本語版の使用経験2016

    • Author(s)
      近藤真前, 清水謙祐, 五島史行, 北原 糺, 今井貴夫, 橋本 誠, 下郡博明, 池園哲郎, 中山明峰
    • Journal Title

      Equilibrium Research

      Volume: 75 Pages: 489-497

    • NAID

      130005310309

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Presentation] Development of real-time video-oculography using high quality infrared video Frenzel, yVOG-Glass2019

    • Author(s)
      Makoto Hashimoto,Yosuke Okinaka,Hironori Fujii,Kazuma Sugahara,Yoshinobu Hirose,Shunsuke Tarumoto,Takuo Ikeda,Hiroshi Yamashita
    • Organizer
      42nd ARO Annual MidWinter Meeting Baltimore
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 頭位センサーと高速度カメラを搭載したyVOG-Glassの有用性2019

    • Author(s)
      橋本 誠
    • Organizer
      山口県めまい・難聴治療研究会 冬期セミナー
    • Related Report
      2018 Annual Research Report
  • [Presentation] DEVELOPMENT OF REAL-TIME VIDEO-OCULOGRAPHY AND IMAGE FILING SYSTEM2018

    • Author(s)
      Makoto Hashimoto,Yosuke Okinaka,Hironori Fujii,Kazuma Sugahara,Yoshinobu Hirose ,Hiroshi Yamashita
    • Organizer
      6th East Asian Symposium on Otology Seoul
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of real-time video-oculography using high quality infrared video Frenzel2018

    • Author(s)
      Makoto Hashimoto,Yosuke Okinaka,Hironori Fujii,Kazuma Sugahara,Yoshinobu Hirose,Takuo Ikeda,Hiroshi Yamashita
    • Organizer
      XXX Barany Society Meeting Uppsala
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] めまい診療up to date2018

    • Author(s)
      橋本 誠
    • Organizer
      第5回 KOGA ENT カンファレンス
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 日常めまい診療に有用な軽量赤外線フレンツェル製品による三次元video―oculography2018

    • Author(s)
      橋本 誠,沖中洋介,池田卓生,藤井博則,橋本智子,菅原一真,広瀬敬信,山下裕司
    • Organizer
      第119回 日本耳鼻咽喉科学会総会・学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 三次元video-oculographyを用いたガルバニック前庭刺激に対する眼振の解析2018

    • Author(s)
      沖中洋介,橋本 誠,藤井博則,山下裕司
    • Organizer
      第80回 耳鼻咽喉科臨床学会総会・学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] VOGの近未来予想図2018

    • Author(s)
      橋本 誠
    • Organizer
      第77回 日本めまい平衡医学会総会・学術講演会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 三次元video-oculographyを用いたガルバニック前庭刺激に対する眼球運動の解析2018

    • Author(s)
      沖中洋介,橋本 誠,藤井博則,山下裕司
    • Organizer
      第77回 日本めまい平衡医学会総会・学術講演会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 電気刺激検査2018

    • Author(s)
      橋本 誠,沖中洋介,藤井博則,菅原一真,山下裕司
    • Organizer
      第77回 日本めまい平衡医学会総会・学術講演会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Development of video-oculography using infrared Frenzel with high quality image camera2018

    • Author(s)
      Makoto Hashimoto,Takuo Ikeda,Yosuke Okinaka,Hironori Fujii,Kazuma Sugahara,Yoshinobu Hirose,Hiroshi Yamashita
    • Organizer
      41th ARO Annual MidWinter Meeting
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of original real-time 3D video-oculography and image filing system, yVOG.2017

    • Author(s)
      Makoto Hashimoto,Takuo Ikeda,Hironori Fuji,Kazuma Sugahara,Yoshinobu Hirose,Hiroshi Yamashita
    • Organizer
      40th ARO Annual MidWinter Meeting
    • Place of Presentation
      Baltimore, USA
    • Year and Date
      2017-02-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] リアルタイム三次元解析可能なVideo―oculography 製品と次世代赤外線フレンツェルの開発2017

    • Author(s)
      橋本 誠,池田卓生,沖中洋介,藤井博則,小林由貴,菅原一真,広瀬敬信,竹本洋介,山下裕司
    • Organizer
      第118回日本耳鼻咽喉科学会通常総会・学術講演会
    • Related Report
      2017 Research-status Report
  • [Presentation] 高画質・高速度カメラを搭載した赤外線フレンツェルと Video―oculography 製品の開発2017

    • Author(s)
      橋本 誠,池田卓生,沖中洋介,藤井博則,小林由貴,菅原一真,広瀬敬信,竹本洋介,山下裕司
    • Organizer
      第76回日本めまい平衡医学会総会・学術講演会
    • Related Report
      2017 Research-status Report
  • [Presentation] リアルタイム三次元眼振図表示可能な Video-oculography 製品の開発2016

    • Author(s)
      橋本 誠,池田卓生,藤井博則,小林由貴,菅原一真,広瀬敬信,竹本洋介,山下裕司
    • Organizer
      第75回 日本めまい平衡医学会総会・学術講演会
    • Place of Presentation
      大阪市(大阪国際会議場)
    • Year and Date
      2016-10-27
    • Related Report
      2016 Research-status Report
  • [Presentation] Quantitative Analysis of Nystabmus by the Original Real-Time Video-Oculography and Image Filing System YVOG2016

    • Author(s)
      Makoto Hashimoto,Takuo Ikeda,Hironori Fuji,Kazuma Sugahara,Yoshinobu Hirose,Hiroshi Yamashita
    • Organizer
      29th Barany Sciety Meeting 2016
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2016-06-05
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 普及型赤外線CCD/CMOSカメラで利用可能な動画記録とVideo―oculography製品の開発2016

    • Author(s)
      橋本 誠,藤井博則,小林由貴,菅原一真,広瀬敬信,竹本洋介,池田卓生,山下裕司
    • Organizer
      第117回 日本耳鼻咽喉科学会通常総会・学術講演会
    • Place of Presentation
      名古屋市(名古屋国際会議場)
    • Year and Date
      2016-05-17
    • Related Report
      2016 Research-status Report
  • [Presentation] Quantitative analysis of nystagmus by original real-time video-oculography and image filing system.2016

    • Author(s)
      Makoto Hashimoto, Takuo Ikeda, Hironori Fuji, Kazuma Sugahara, Yoshinobu Hirose, Hiroshi Yamashita
    • Organizer
      39th MidWinter Meeting - Association for Research in Otolaryngology
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2016-02-16
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 普及型赤外線CCD/CMOSカメラで利用可能な動画ファイリングと眼振自動解析ソフトウエア製品の開発2015

    • Author(s)
      橋本 誠、池田 卓生、藤井 博則、菅原 一真、下郡 博明、山下 裕司
    • Organizer
      第74回日本めまい平衡医学会総会・学術講演会
    • Place of Presentation
      岐阜県岐阜市(長良川国際会議場、岐阜都ホテル)
    • Year and Date
      2015-11-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 長期に経過観察を行った中枢性平衡障害の3例2015

    • Author(s)
      藤井 博則、橋本 誠、菅原 一真、池田 卓生、下郡 博明、山下 裕司
    • Organizer
      第74回日本めまい平衡医学会総会・学術講演会
    • Place of Presentation
      岐阜県岐阜市(長良川国際会議場、岐阜都ホテル)
    • Year and Date
      2015-11-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 抗うつ薬慢性摂取動物モデルの検討2015

    • Author(s)
      下郡 博明、坂本 茉理、藤井 博則、橋本 誠、菅原 一真、山下 裕司
    • Organizer
      第74回日本めまい平衡医学会総会・学術講演会
    • Place of Presentation
      岐阜県岐阜市(長良川国際会議場、岐阜都ホテル)
    • Year and Date
      2015-11-25
    • Related Report
      2015 Research-status Report
  • [Presentation] 日常診療における眼振動画の記録管理とvideo-oculography2015

    • Author(s)
      橋本 誠、池田 卓生、藤井 博則、菅原 一真、下郡 博明、山下 裕司
    • Organizer
      第77回耳鼻咽喉科臨床学会総会・学術講演会
    • Place of Presentation
      静岡県・浜松市(オークラアクトシティホテル浜松、アクトシティ浜松)
    • Year and Date
      2015-06-25
    • Related Report
      2015 Research-status Report
  • [Book] 「イラスト」めまいの検査2018

    • Author(s)
      日本平衡神経科学会
    • Total Pages
      192
    • Publisher
      診断と治療社
    • ISBN
      4787823256
    • Related Report
      2018 Annual Research Report

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Published: 2015-04-16   Modified: 2020-03-30  

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