| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
On 26 patients performed ABCC11 genotyping ,dry earwax with 538A/A and wet earwax with 538G/A were 53.8%(14/26) and 46.2%(12/26). Wet earwax with538G/G was none. Concerning the incidence of cases with bilateral middle ear cholesteatoma (including past history of surgery of middle ear cholesteatoma), a group of wet earwax 58.8%(7/12) showed higher than dry earwax 21.6(3/14), but not significance due to small number (26 patients performed ABCC11 genotyping).
40 patients (26 patients with ABCC11 genotyping and 14 patients with middle ear cholesteatoma were decided earwax in healthy side by only inspection ) were analyzed as follows(Table 2). The frequencies of dry earwax and wet earwax were 62.5%(25/40) and 32.4%(15/40). Wet earwax with538G/G was none. The incidence of cases with bilateral middle ear cholesteatoma (including past history of surgery of middle ear cholesteatoma), a group of wet earwax 66.7%(7/15 ) showed significantly higher than dry earwax 24.0(6/25)（P<0.05）.
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