| Project/Area Number |
15K10797
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
福光 延吉 神戸大学, 医学研究科, 客員准教授 (40277075)
大西 かよ子 筑波大学, 医学医療系, 講師 (60529832)
石川 仁 筑波大学, 医学医療系, 教授 (70344918)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | ホウ素中性子捕捉療法 / 頭頸部癌 / 18F-BPA-PET / 補助療法 / ホウ素中性子補足療法 |
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| Outline of Final Research Achievements |
BNCT was performed on patients with recurrent refractory head and neck cancer at the University of Tsukuba and chemotherapy or molecular targeting therapy according to each tissue type was added as adjuvant therapy from 4 weeks after irradiation. As a result, the average survival time of 4 cases was 12 months, which was slightly longer than that of the conventional similar report. Although statistical analysis was not possible due to the small number of cases, BNCT for head and neck cancer suggested that prolongation of life prognosis could be prolonged by adding adjuvant therapy according to case after irradiation.
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