Temperature alteration in the anterior chamber and corneal endothelium injury during phacoemulsification
Project/Area Number |
15K10851
|
Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Ophthalmology
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Research Institution | Nippon Medical School |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
高橋 浩 日本医科大学, 医学(系)研究科(研究院), 教授 (00188046)
五十嵐 勉 日本医科大学, 医学部, 准教授 (10421190)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 白内障手術 / 超音波乳化吸引術 / 角膜内皮障害 / 前房温度 / 切開創温度 / 角膜内皮温度 / 粘弾性物質 / 眼内圧 / 白内障 / 手術 |
Outline of Final Research Achievements |
Phacoemulsification (PEA)is the most popular surgery for cataracts in the world. However,corneal endothelial damage still represents a serious complication, as excessive damage can lead to irreversible bullous keratopathy.The corneal endothelium can be damaged during PEA by various factors including localized temperature increases. As the evaluation of the cornea endothelium damage in the temperature rise test during PEA, the anterior chamber temperature and the cornea endothelium temperature were measured at the same time using pig eyes. During simulated phacoemulsification in porcine eyes, aqueous humor temperature was measured by use of a temperature probe set in the anterior chamber filled with the viscoelastics. Viscoelastics can hinder adequate water circulation in the anterior chamber and induce temperature rise. Surgeons should pay attention to viscoelastic-related temperature rise in the aqueous humor during PEA.
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Report
(4 results)
Research Products
(1 results)