| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
In this study, precise mechanism of angiogenesis in the intraocular neovascularization in ischemic and hypertensive environments is studied. The goal is to elucidate the mechanism and develop into future treatment, and the retinal blood flow is measured by Laser speckle flowgraphy. Reduction of VEGF by retinal photocoagulation significantly reduces ocular fundus blood flow and improves the activity of retinal neovascularization.
It is suggested that the possibility to quantify effective retinal photocoagulation by measuring its blood flow decrease the activity of neovascularization.
It is necessary to investigate the involvement of succinate in fundus blood flow.
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