| Project/Area Number |
15K10925
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | Kyushu University |
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Principal Investigator |
Esumi Genshiro 九州大学, 医学研究院, 共同研究員 (30452759)
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| Co-Investigator(Kenkyū-buntansha) |
松浦 俊治 九州大学, 医学研究院, 講師 (10532856)
林田 真 九州大学, 医学研究員, 共同研究員 (70452761)
田口 智章 九州大学, 医学研究院, 教授 (20197247)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | TARC / 移植 / 免疫抑制マーカー / 肝移植 / FK506 / 免疫抑制 / マーカー / 拒絶 / アレルギー / タクロリムス / 食物アレルギー / 臓器移植 |
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| Outline of Final Research Achievements |
The aim of this study is to evaluate serum TARC measurement as immune suppression marker for solid organ transplantation recipients. Trough of FK-506, which is indirect marker and now widely used, do not directly indicate immune suppression statues, and sometimes it is not easy to keep and control immune suppression status in desirable level. In this research, serum TARC level partially correlate graft rejection and auto immune hepatitis episodes, but more correlate with their dermatitis. The validity of using TARC for immune suppression marker was concluded to be limited.
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