| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
The wound healing was promoted when the MUSE (Multi-lineage differentiating stress enduring) cells were transplanted into the skin ulcer of rat. And the degree of wound healing was almost equal to the case of the BMSC (Bone marrow stromal cell) transplantation. In addition, the MUSE cells and the BMSCs couldn't be recognized in the tissues of the wound 14days after cell transplantation. There was the possibility that a paracrine effect primarily promoted the healing of cutaneous wounds.
By culturing the MUSE cells of rat, lesser cell proliferation was recognized when they were cultured in culture fluid with autologous serum than with FBS.
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