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Association among inflammation, delirium, and sleep by sleep monitor in critically ill patients

Research Project

Project/Area Number 15K10981
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Emergency medicine
Research InstitutionYamaguchi University

Principal Investigator

TSURUTA Ryosuke  山口大学, 大学院医学系研究科, 教授 (30263768)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords脳波 / レム睡眠 / Richards-Campbell睡眠質問票 / 睡眠 / 炎症 / ICU / 睡眠脳波 / 回復期 / 重症疾患 / REM睡眠
Outline of Final Research Achievements

The ICU patients were recorded electroencephalography (EEG) in the recovery phase using single channel EEG. We analyzed the sleep stages by frequency analysis. The sleep EEG recordings were obtained from 16 patients, with median (interquartile range) age of 64 (48-78) and male of 11. The diagnoses were trauma of 6, infection of 3, aortic dissection of 3, accidental hypothermia of 2, and others of 2 patients. Serum C-reactive protein (CRP) and Richards-Campbell sleep questionnaire (RCSQ) on the recording day were 7.1(3.3-13.0)mg/dl and 340(260-410). The patients were divided into 2 groups by 10% of %REM. Less than 10% of %REM had a greater tendency of higher CRP and lower RCSQ, which were not statistically significant.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2017

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] 重症患者の睡眠管理2017

    • Author(s)
      鶴田良介、山本隆裕、藤田基
    • Journal Title

      日本集中治療医学会雑誌

      Volume: 24 Pages: 389-97

    • NAID

      130005709553

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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