| Project/Area Number |
15K11078
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Nagasaki University |
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Principal Investigator |
SUMI Misa 長崎大学, 医歯薬学総合研究科(歯学系), 准教授 (90284702)
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| Co-Investigator(Kenkyū-buntansha) |
中村 卓 長崎大学, 医歯薬学総合研究科(歯学系), 教授 (30172406)
佐々木 美穂 長崎大学, 病院(歯学系), 助教 (10437874)
高木 幸則 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (30295084)
榮田 智 長崎大学, 医歯薬学総合研究科(歯学系), 助教 (80325662)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | DWI / 高b値DWI / 拡散強調像 / 拡散強調MRI |
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| Outline of Final Research Achievements |
Diffusion-weighted MR imaging (DWI) reflects the differences in the rate of diffusion of water molecules. The contrast of the image depends on the b-value representing the magnitude of the gradient magnetic field, and if the b-value is set high, the motion of the slow water molecule is targeted for imaging. Therefore, DWI (high b-value DWI) using the high b value is expected to provide information on the microstructure of the cells that could not be obtained with conventional images.
In this study, low to high multiple b-value DWI was performed on patients with various head and neck tumors, and the various parameters obtained were compared with the pathological tissues. As a result, it was suggested the usefulness of high b-value DWI in head and neck tumor diagnosis.
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