| Project/Area Number |
15K11092
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Matsumoto Dental University |
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Principal Investigator |
Taguchi Akira 松本歯科大学, 歯学部, 教授 (70243582)
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| Co-Investigator(Kenkyū-buntansha) |
吉成 伸夫 松本歯科大学, 歯学部, 教授 (20231699)
東 幸仁 広島大学, 原爆放射線医科学研究所, 教授 (40346490)
浅野 晃 関西大学, 総合情報学部, 教授 (60243987)
三木 学 松本歯科大学, 歯学部, 助手 (80549410)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 骨粗鬆症 / パノラマエックス線写真 / スクリーニング / 血管 / 骨梁解析 / 頸動脈石灰化 / 歯槽骨吸収 / 歯科 / 骨折 / 血管内皮機能 / 総頸動脈石灰化 / パノラマエックス線謝写真 |
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| Outline of Final Research Achievements |
The odds ratios for an osteoporosis diagnosis associated with mildly to moderately and severely eroded mandibular cortices on panoramic radiographs were 2.5 (95％ confidence interval [CI], 1.7-3.8) and 3.8 (95% CI, 2.4-6.1), respectively. However, there was no significant association between osteoporosis diagnosis and trabecular pattern of alveolar bone analyzed by both visually and image processing, indicating that trabecular pattern of alveolar bone cannot be used for identifying individuals with undetected osteoporosis. On the other hand, the odds ratios for an osteoporosis diagnosis associated with the history of hypertension and self-reported kyphosis were 1.5 (95% CI, 1.1-2.0) and 4.2 (95% CI, 1.8 to 9.5), respectively. These clinical informations may increase the diagnostic performance for identifying individuals with undetected osteoporosis. Unfortunately, number of teeth presence and the degree of alveolar bone resorption were not associated with an osteoporosis diagnosis.
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