Construction of the new osteoporosis screening system which unified indices detected on oral and maxillofacial image
Project/Area Number |
15K11092
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Pathobiological dentistry/Dental radiology
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Research Institution | Matsumoto Dental University |
Principal Investigator |
Taguchi Akira 松本歯科大学, 歯学部, 教授 (70243582)
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Co-Investigator(Kenkyū-buntansha) |
吉成 伸夫 松本歯科大学, 歯学部, 教授 (20231699)
東 幸仁 広島大学, 原爆放射線医科学研究所, 教授 (40346490)
浅野 晃 関西大学, 総合情報学部, 教授 (60243987)
三木 学 松本歯科大学, 歯学部, 助手 (80549410)
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Project Period (FY) |
2015-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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Keywords | 骨粗鬆症 / パノラマエックス線写真 / スクリーニング / 血管 / 骨梁解析 / 頸動脈石灰化 / 歯槽骨吸収 / 歯科 / 骨折 / 血管内皮機能 / 総頸動脈石灰化 / パノラマエックス線謝写真 |
Outline of Final Research Achievements |
The odds ratios for an osteoporosis diagnosis associated with mildly to moderately and severely eroded mandibular cortices on panoramic radiographs were 2.5 (95% confidence interval [CI], 1.7-3.8) and 3.8 (95% CI, 2.4-6.1), respectively. However, there was no significant association between osteoporosis diagnosis and trabecular pattern of alveolar bone analyzed by both visually and image processing, indicating that trabecular pattern of alveolar bone cannot be used for identifying individuals with undetected osteoporosis. On the other hand, the odds ratios for an osteoporosis diagnosis associated with the history of hypertension and self-reported kyphosis were 1.5 (95% CI, 1.1-2.0) and 4.2 (95% CI, 1.8 to 9.5), respectively. These clinical informations may increase the diagnostic performance for identifying individuals with undetected osteoporosis. Unfortunately, number of teeth presence and the degree of alveolar bone resorption were not associated with an osteoporosis diagnosis.
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Report
(4 results)
Research Products
(59 results)
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[Journal Article] Efficacy and safety of once-yearly zoledronic acid in Japanese patients with primary osteoporosis: Two-year results from a randomized placebo-controlled double-blind study (ZOledroNate treatment in Efficacy to osteoporosis; ZONE Study)2017
Author(s)
Nakamura T, Fukunaga M, Nakano T, Kishimoto H, Ito M, Hagino H, Sone T, Taguchi A, Tanaka S, Ohashi M, Ota Y, Shiraki M
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Journal Title
Osteoporos Int
Volume: 28
Issue: 1
Pages: 389-398
DOI
Related Report
Peer Reviewed
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[Journal Article] Increasing Risk of Osteoporotic Fracture Is Associated With Vascular Dysfunction and Abnormal Vascular Structure in Both Men and Women2017
Author(s)
Kajikawa M, Oda N, Kishimoto S, Maruhashi T, Iwamoto Y, Iwamoto A, Matsui S, Aibara Y, Mohamad Yusoff FB, Hidaka T, Kihara Y, Chayama K, Goto C, Noma K, Nakashima A, Taguchi A, Higashi Y
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Journal Title
Circulation Journal
Volume: 81
Issue: 6
Pages: 862-869
DOI
NAID
ISSN
1346-9843, 1347-4820
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Antiresorptive agent-related osteonecrosis of the jaw: Position Paper 2017 of the Japanese Allied Committee on Osteonecrosis of the Jaw.2017
Author(s)
Japanese Allied Committee on Osteonecrosis of the Jaw, Yoneda T, Hagino H, Sugimoto T, Ohta H, Takahashi S, Soen S, Taguchi A, Nagata T, Urade M, Shibahara T, Toyosawa S.
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Journal Title
J Bone Miner Metab
Volume: 35(1)
Issue: 1
Pages: 6-19
DOI
Related Report
Peer Reviewed
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[Journal Article] Osteoporosis, osteoporotic fractures, and carotid artery calcification detected on panoramic radiographs in Japanese men and women2016
Author(s)
Iwamoto Y, Uchida K, Sugino N, Kuroiwa H, Kitamura Y, Udagawa N, Shinohara A, Higashi Y, Taguchi A
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Journal Title
Oral Surg Oral Med Oral Pathol Oral Radiol
Volume: 121
Issue: 6
Pages: 673-680
DOI
Related Report
Peer Reviewed / Acknowledgement Compliant
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[Journal Article] Delayed wound healing after tooth extraction and self-reported kyphosis in Japanese men and women2016
Author(s)
Taguchi A, Kamimura M, Nakamura Y, Sugino N, Ichise A, Maezumi H, Fukuzawa K, Ashizawa R, Takahara K, Gushiken S, Mukaiyama K, Ikegami S, Uchiyama S, Kato H
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Journal Title
Sci Rep
Volume: -
Issue: 1
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Comparing immunocompetent and immunodeficient mice as ectopic transplantation animal models for bone tissue engineering2015
Author(s)
Zhang Y, Li X, Chihara T, Mizoguchi T, Hori A, Udagawa N, Takahashi N, Nakamura H, Hasegawa H, Taguchi A, Shinohara A, Kagami H
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Journal Title
Oral Diseases
Volume: 21
Issue: 5
Pages: 583-592
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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