Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Outline of Final Research Achievements |
In this study an in vitro root caries induction model system was constructed to develop a new treatment for inhibition of progression of root caries. Using this model system, we investigated the influence on root caries progression bacteria dynamics of the carious lesion by strains and the culture conditions of cariogenic bacteria. The results showed that three Actinomyces species, A. naeslundii, A. viscosus, and A. israelii, possessed different characteristics on the pathology and the mechanisms of root caries progression.
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