Establishment of bone quality improvement therapy using intelligent artificial bone
Project/Area Number |
15K11160
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Prosthodontics/ Dental materials science and
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Research Institution | Hiroshima University |
Principal Investigator |
DOI KAZUYA 広島大学, 医歯薬保健学研究科(歯), 助教 (80444686)
|
Co-Investigator(Kenkyū-buntansha) |
岡崎 洋平 広島大学, 病院(歯), 助教 (00706898)
日浅 恭 広島大学, 病院(歯), 講師 (60304432)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | PTH / 骨粗鬆症 / 骨質 |
Outline of Final Research Achievements |
In this study, bone quality improvement therapy using combination methods of intelligent arterial bone: polyphosphate integrated porous HA and intermittent PTH administration was assessment under conditions of reduced bone quality and metabolism. The combination methods indicated the promotion of osteoblast activation, enhancement bone formation and establishment implant stability: preferable primary stability and achievement osseointegration in rabbit osteoporosis model.
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Report
(4 results)
Research Products
(12 results)
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[Journal Article] A stability evaluation of a novel titanium dental implant/interconnected porous hydroxyapatite complex under functional loading conditions2017
Author(s)
Doi K, Kubo T, Kajihara S, Makihara Y, Oue H, Oki Y, Perrotti V, Piattelli A, Akagawa Y, Tsuga K
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Journal Title
Dental Materials Journal
Volume: 36
Issue: 5
Pages: 647-653
DOI
NAID
ISSN
0287-4547, 1881-1361
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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