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The assessment of the pharyngeal residue using retro-nasal

Research Project

Project/Area Number 15K11194
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionNiigata University

Principal Investigator

HORI Kazuhiro  新潟大学, 医歯学系, 准教授 (70379080)

Co-Investigator(Kenkyū-buntansha) 井上 誠  新潟大学, 医歯学系, 教授 (00303131)
小野 高裕  新潟大学, 医歯学系, 教授 (30204241)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords嚥下 / 咽頭残留 / 香料 / 嚥下障害 / レトロネーザル / 舌圧
Outline of Final Research Achievements

Pharyngeal residue after swallowing may be due to weak pharyngeal pressure, dyscoordination of swallow-related muscle activity. Retro-nasal aroma is defined as the sensory perception of aroma via velo-pharynx. In the present study, we test the hypothesis that pharyngeal residue can be quantified by measurement of retro-nasal aroma.
Since the simulation of pharyngeal residue, flavor essence was ingested to hypo pharynx via catheter and the subjects was asked to hold the test sample and not to swallow. The intensity of retro-nasal was measured via nasal tube from naris using odor sensor.
The intensity of retro-nasal was increased gradually and reached plateau 60 second after ingestion. Furthermore, it had a significant liner correlation with the amount of the flavor essence. These results were obtained at the simulation of pharyngeal residue after swallowing. These results suggested the possibility of the quantitative assessment of pharyngeal residue.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (31 results)

All 2018 2017 2016 2015 Other

All Int'l Joint Research (1 results) Journal Article (16 results) (of which Int'l Joint Research: 4 results,  Peer Reviewed: 15 results,  Open Access: 4 results) Presentation (14 results) (of which Int'l Joint Research: 6 results,  Invited: 4 results)

  • [Int'l Joint Research] ウィスコンシン大学(米国)

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Effects of pharyngeal electrical stimulation on swallowing performance2018

    • Author(s)
      Takeishi Ryosuke、Magara Jin、Watanabe Masahiro、Tsujimura Takanori、Hayashi Hirokazu、Hori Kazuhiro、Inoue Makoto
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 1 Pages: e0190608-e0190608

    • DOI

      10.1371/journal.pone.0190608

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Effect of bolus volume and flow time on temporospatial coordination in oropharyngeal pressure production in healthy subjects2018

    • Author(s)
      Yano Jitsuro、Aoyagi Yoichiro、Ono Takahiro、Hori Kazuhiro、Yamaguchi Wakami、Fujiwara Shigehiro、Kumakura Isami
    • Journal Title

      Physiology & Behavior

      Volume: 189 Pages: 92-98

    • DOI

      10.1016/j.physbeh.2018.03.006

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Immediate effect of laryngeal surface electrical stimulation on swallowing performance2018

    • Author(s)
      Takahashi Keizo、Hori Kazuhiro、Hayashi Hirokazu、Fujiu-Kurachi Masako、Ono Takahiro、Tsujimura Takanori、Magara Jin、Inoue Makoto
    • Journal Title

      Journal of Applied Physiology

      Volume: 124 Issue: 1 Pages: 10-15

    • DOI

      10.1152/japplphysiol.00512.2017

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationships between dysphagia and tongue pressure during swallowing in Parkinson's disease patients.2018

    • Author(s)
      Minagi Y, Ono T, Hori K, Fujiwara S, Tokuda Y, Murakami K, Maeda Y, Sakoda S, Yokoe M, Mihara M, Mochizuki H.
    • Journal Title

      Journal of oral rehabilitation

      Volume: in press Issue: 6 Pages: 459-466

    • DOI

      10.1111/joor.12626

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of water viscosity and tongue ingestion site on tongue pressure during food bolus propulsion2018

    • Author(s)
      Iguchi T.、Ohkubo M.、Sugiyama T.、Hori K.、Ono T.、Ishida R.
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 45 Issue: 5 Pages: 371-377

    • DOI

      10.1111/joor.12623

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of carrot puree in vegetable juice on linguapalatal swallowing pressure2017

    • Author(s)
      Moritaka Hatsue、Mineki Machiko、Kobayashi Makoto、Ono Takahiro、Hori Kazuhiro
    • Journal Title

      Journal of Texture Studies

      Volume: 49 Issue: 2 Pages: 240-246

    • DOI

      10.1111/jtxs.12315

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Measurement of swallowing by monitoring thyroid cartilage movement in healthy subjects using thickened liquid samples and its comparison with sensory evaluation2017

    • Author(s)
      Funami T, Matsuyama S, Ikegami A, Nakauma M, Hori K, Ono T
    • Journal Title

      J Texture Stud

      Volume: 印刷中 Issue: 6 Pages: 494-506

    • DOI

      10.1111/jtxs.12261

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Tongue Pressure Production and Submental Surface Electromyogram Activities During Tongue-Hold Swallow with Different Holding Positions and Tongue Length2017

    • Author(s)
      Fujiwara Shigehiro、Fujiu-Kurachi Masako、Hori Kazuhiro、Maeda Yoshinobu、Ono Takahiro
    • Journal Title

      Dysphagia

      Volume: 印刷中 Issue: 4 Pages: 403-413

    • DOI

      10.1007/s00455-017-9865-4

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The biomechanical coordination during oropharyngeal swallowing: an evaluation with a non-invasive sensing system.2017

    • Author(s)
      Li Q, Minagi Y, Ono T, Chen Y, Hori K, Fujiwara S, Maeda Y.
    • Journal Title

      Scientific reports

      Volume: 7 Issue: 1 Pages: 15243-6

    • DOI

      10.1038/s41598-017-15243-6

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 長期経過における機能変化への対応を考える2016

    • Author(s)
      堀 一浩
    • Journal Title

      顎顔面補綴

      Volume: 39 Pages: 95-97

    • NAID

      130008045485

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Importance of professional oral hygiene in preventing medication-related osteonecrosis of the jaw2016

    • Author(s)
      Ohnishi Y, Ito K, Kitamura R, Funayama S, Hori K, Inoue M
    • Journal Title

      IJOMS

      Volume: 15 Pages: 85-92

    • NAID

      130006894943

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 舌接触補助床(Palatal Augmentation Prosthesis)2016

    • Author(s)
      小野高裕,堀一浩
    • Journal Title

      日本歯科医歯学会雑誌

      Volume: 69 Pages: 14-17

    • Related Report
      2016 Research-status Report
    • Peer Reviewed
  • [Journal Article] Tongue pressure production during swallowing in patients with mandibular prognathism2016

    • Author(s)
      Sakaue K, Fukui T, Sasakura C, Hori K, Ono T, Saito I
    • Journal Title

      J Oral Rehabil

      Volume: 43 Issue: 5 Pages: 348-355

    • DOI

      10.1111/joor.12379

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Throat sensations of beverages evaluated by in vivo measurements of swallowing2015

    • Author(s)
      Funami T, Isono M, Ikegami A, Nakao S, Nakauma M, Fujiwara S, Minagi Y, Hori K, Ono T
    • Journal Title

      J Texture Stud

      Volume: 46 Issue: 3 Pages: 187-199

    • DOI

      10.1111/jtxs.12111

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Coordination in oro-pharyngeal biomechanics during human swallowing2015

    • Author(s)
      Li Q, Minagi Y, Hori K, Kondoh J, Fujiwara S, Tamine K, Inoue M, Maeda Y, Chen Y, Ono T
    • Journal Title

      Physiol Behav

      Volume: 147 Pages: 300-305

    • DOI

      10.1016/j.physbeh.2015.05.004

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] 新しい評価ツールへの期待2015

    • Author(s)
      小野高裕, 堀 一浩, 藤原茂弘
    • Journal Title

      嚥下医学

      Volume: 4 Pages: 178-181

    • Related Report
      2015 Research-status Report
  • [Presentation] The dynamics of Retro-Nasal during chewing2018

    • Author(s)
      Okawa J, Hori K, Salazar S, Ono T
    • Organizer
      International Symposium on Development of Human Resources in Practical Oral Health and Treatment
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Coordination of oro-pharyngeal pressures during swallowing2018

    • Author(s)
      Hori K, Jones C, Rosen S, Abdelhalim S, McCulloch T
    • Organizer
      Research Summit 2018
    • Related Report
      2017 Annual Research Report
  • [Presentation] Evaluation of pharyngeal residue after swallowing using odor sensor2017

    • Author(s)
      Okawa J, Hori K, Fujiwara S, Uehara F, Ono T
    • Organizer
      Collaborative Symposium Faculty of Dentistry Prince of Songkla University - Niigata University
    • Place of Presentation
      Samui, Thailand
    • Year and Date
      2017-02-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] 咀嚼中のレトロネーザルの動態を探る2017

    • Author(s)
      大川純平, 堀 一浩, Simonne E. Salazar, 小野高裕
    • Organizer
      第28回日本咀嚼学会学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 液体嚥下時における舌圧と咽頭への食塊移送との関連2017

    • Author(s)
      大川純平, 兒玉匠平, 上原文子, 設楽仁子, 堀 一浩, 小野高裕
    • Organizer
      第23回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 舌接触補助床(PAP)による嚥下機能の回復2016

    • Author(s)
      堀一浩
    • Organizer
      第2回補綴歯科臨床研鑽会プロソ’16
    • Place of Presentation
      ベルサール新宿(東京都)
    • Year and Date
      2016-12-10
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] センサシートで診る舌の動き2016

    • Author(s)
      堀一浩
    • Organizer
      第23回日本歯科医学会総会
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2016-10-21
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] ニオイセンサによる嚥下後咽頭残留の推定2016

    • Author(s)
      大川純平,堀 一浩,藤原茂弘,上原文子,小野 高裕
    • Organizer
      日本顎口腔機能学会第57回学術大会
    • Place of Presentation
      東北大学(仙台市)
    • Year and Date
      2016-10-02
    • Related Report
      2016 Research-status Report
  • [Presentation] 香料を用いた嚥下後咽頭残留の定量的評価の試み2016

    • Author(s)
      大川純平,堀 一浩,藤原茂弘,上原文子,小野 高裕
    • Organizer
      第22回日本摂食嚥下リハビリテーション学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Research-status Report
  • [Presentation] Tongue pressure measurement and rehabilitation using palatal augmentation prosthesis for glossectomy patients2016

    • Author(s)
      Hori K
    • Organizer
      第22回日本摂食嚥下リハビリテーション学会 日韓合同シンポジウム
    • Place of Presentation
      朱鷺メッセ(新潟市)
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Tongue muscle pressure and swallowing control2015

    • Author(s)
      Hori K
    • Organizer
      International Conference on Food for Elderly
    • Place of Presentation
      Hangzhou(China)
    • Year and Date
      2015-10-16
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Assessment of pharyngeal residue using retro-nasal aroma2015

    • Author(s)
      Hori K, Fujiwara S, Inoue M, Ono T
    • Organizer
      5th Congress of European Society for Swallowing Disorder
    • Place of Presentation
      Barcelona(Spain)
    • Year and Date
      2015-10-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 香料を用いた咽頭残留の定量評価の試み2015

    • Author(s)
      堀 一浩, 藤原茂弘,大川純平,井上 誠,小野高裕
    • Organizer
      第21回摂食嚥下リハビリテーション学会
    • Place of Presentation
      京都国際会館(京都府・京都市)
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
  • [Presentation] 摂食嚥下リハビリテーションとFood Oral Processing2015

    • Author(s)
      堀 一浩
    • Organizer
      日本食品科学工学会 第62回大会
    • Place of Presentation
      京都大学(京都府・京都市)
    • Year and Date
      2015-08-29
    • Related Report
      2015 Research-status Report
    • Invited

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Published: 2015-04-16   Modified: 2022-06-07  

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