| Project/Area Number |
15K11200
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Nihon University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 閉塞性睡眠時無呼吸症 / 口腔内装置 / 舌小帯 / 睡眠時無呼吸症 / 咽頭気道 / 睡眠時無呼吸 / 下顎前方位型 / 咽頭軌道 / 舌 / 閉塞型睡眠時無呼吸症 / 舌小帯押板 / 咽頭閉塞 |
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| Outline of Final Research Achievements |
Oral appliances (OAs) for obstructive sleep apnea (OSA) treatments are very effective. However, the forces generated by OAs can lead to a reduction in overjet and overbite, which can cause changes in dental occlusion during long-term treatment in patients with OSA. We hypothesized that changing the shape of the tongue and securing an airway between the dorsum of the tongue and soft palate without advancing the mandible would alleviate OSA symptoms. Therefore, we investigated the efficacy of an OA equipped with a lingual frenulum depressor (LFD) in patients with OSA.
In result, significant improvements in 3%ODI, SpO2min, and ESS score were observed following the use of the OA with LFD device at both 2 weeks and 3 months.To achieve this aim, we examined how changes in the shape of the tongue due to a novel OA equipped with an LFD would impact OSA. Our findings suggest that the OA with LFD represents a novel alternative to CPAP therapy and advancement of the mandible in patients with OSA.
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