| Project/Area Number |
15K11217
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
ESAKI DAISUKE 九州大学, 歯学研究院, 助教 (10608970)
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| Co-Investigator(Kenkyū-buntansha) |
松下 恭之 九州大学, 大学病院, 准教授 (60159150)
三浦 真由美 九州大学, 大学病院, 学術研究員 (00404054)
古谷野 潔 九州大学, 歯学研究院, 教授 (50195872)
大木 郷資 九州大学, 大学病院, 医員 (10803463)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | インプラント周囲炎 / 殺菌 / 過硝酸 / 治療 |
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| Outline of Final Research Achievements |
The purpose of this study was to investigate the bactericidal effect of Peroxynitric acid on the biofilm cultured on titanium surface. Streptococcus gordonii (ATCC 10558 ) was cultured on a titanium disc with NS, 0.025% BZC, 0.2% CHX, 4.6 mmol / L PNA, and 4.6 mmol / L of PNA whichwas left standing at 25 ° C-24 hour to inactivate bactericidal activity These seven type of chemical solution were compared with bactericidal effec . As a result of the CFU assay, in PNA, the number of bacteria was less than the detection limit at an action time of 10 seconds. Compared with other disinfectants, it was suggested that PNA is useful for sterilizing bacterially contaminated titanium surfaces.
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