| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
This study aimed to evaluate atmospheric low temperature plasma as a basic research for the development of technology that can non-invasively sterilize regenerated transplanted tissues and host recipient tissues. It was verified that the active species produced by the plasma show sufficient bactericidal activity and that the activity disappears in a short time and does not show residual activity.
In the verification of the infection model, plasma treated water showed a very high effect in a shorter time than the irradiation method. As a result of conducting a safety test of plasma treated water in a graft recipient tissue and transplanted cell (monolayer cell and graft tissue sheet) model, no metabolic activity failure was observed, and high safety was shown.
Therefore, it was concluded that plasma-treated water has high bactericidal activity and biological tissue safety.
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