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Establishment of a new method for healing of tooth extraction by immediate implantation of extracted tooth pulp tissue

Research Project

Project/Area Number 15K11279
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Surgical dentistry
Research InstitutionTsurumi University

Principal Investigator

TOKUYAMA Reiko  鶴見大学, 歯学部, 学内講師 (20380090)

Co-Investigator(Kenkyū-buntansha) 里村 一人  鶴見大学, 歯学部, 教授 (80243715)
井出 信次  鶴見大学, 歯学部, 非常勤講師 (00611998)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords抜歯窩治癒促進法 / 歯髄組織 / 抜歯窩治癒促進 / 歯髄
Outline of Final Research Achievements

Mandibular horizontal impaction tooth is one of the most common surgical procedures encountered in oral surgery clinic. In this study, we examined whether or not it is possible to promote healing of tooth extraction cavity by extracting dental pulp tissue from extracted teeth immediately after tooth extraction and transplanting to tooth extraction cavity just after tooth extraction of mandibular horizontal impacted tooth. Both sides of upper first molar of the mouse were extracted. The pulp tissue was removed from this extracted tooth and after implantation in the extraction tooth cavity, the healing process was observed histologically time dependent. As a result, on the dental pulp tissue transplant side, there was a tendency to promote healing, but there was no obvious significant difference. In the future, we plan to investigate using scaffold-based substrates when transplanting dental pulp tissue.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2016

All Presentation (1 results)

  • [Presentation] 歯髄幹細胞の効率的回収を可能とする新規凍結保存法の開発2016

    • Author(s)
      竹部祐生亮、舘原誠晃、今村武浩、福島龍洋、戸田(徳山)麗子、里村一人
    • Organizer
      第26回日本口腔内科学会・第29回日本口腔診断学会合同学術大会
    • Place of Presentation
      さん太ホール(岡山県岡山市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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