| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
To solve the problems concerning residues in the body and strength of the biomaterials, we performed a research of a next generation reconstruction method using biogradable magnesium alloy mesh and got the next results. 1. The living body safety was confirmed by in vitro cell toxicological test of a containing element and in vivo rat back subcutaneous transplantation. But the hydrogen gassing was confirmed by the absorption process. 2. Development of a bone transplantation fixed way by a biodegradablility magnesium alloy pin: A magnesium alloy pin of transplantation bone fixing (Mg pin) has been developed. It was possible to fix a bone fragment for 24 weeks by a Mg pin by an experiment of rabbit.No complications were observed in a follow up period for 6 months postoeprtively, and the healing process was excellent. Control of hydrogen gas which occurs in an absorption early stage of a Mg pin and consideration of surface design of the Mg pin seemed to be necessary.
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