The Bone Regenerative effect of Osteoblasts on Novel Hydroxyapatite Ceramics and Study for Clinical application
Project/Area Number |
15K11314
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Surgical dentistry
|
Research Institution | Hiroshima University |
Principal Investigator |
TADA MISATO 広島大学, 病院(歯), 歯科診療医 (40572326)
|
Co-Investigator(Kenkyū-buntansha) |
武知 正晃 広島大学, 医歯薬保健学研究科(歯), 准教授 (00304535)
二宮 嘉昭 広島大学, 病院(歯), 助教 (60335685)
重石 英生 広島大学, 医歯薬保健学研究科(歯), 講師 (90397943)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 多孔質セラミックス / 骨再建材料 / 骨芽細胞 / ハイドロキシアパタイト / 培養人工骨 / 生体材料 |
Outline of Final Research Achievements |
Interconnected Porous Calcium Hydroxyapatite (IP-CHA) is an excellent ceramic for use in bone tissue engineering because of its fully interconnected porous structure, which allows osteoblasts disperion and supports their osteogenic differentiation. this study provided biochemical evidence that IP-CHA/osteoblasts composite and IP-CHA/osteoblasts/growth facters composite could enhance osteogenic potential. It was strongly suggested that IP-CHA was a useful biomaterials for bone tissue regeneration.
|
Report
(4 results)
Research Products
(14 results)
-
-
-
[Journal Article] Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients.2016
Author(s)
Shigeishi H, Ohta K, Fujimoto S, Nakagawa T, Mizuta K, Ono S, Shimasue H, Ninomiya Y, Higashikawa K, Tada M, Ishida F, Takechi M.
-
Journal Title
Exp Ther Med
Volume: 12(3)
Pages: 1922-1928
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-