Development of new bone prosthetic material using iPS cell and phosphorylated pullulan
| Project/Area Number |
15K11336
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
山本 照子 東北大学, 歯学研究科, 名誉教授 (00127250)
竹下 信郎 東北大学, 歯学研究科, 助教 (50431515)
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| Research Collaborator |
TAKUMI OKIHARA
YASUHIRO YOSHIDA
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 歯学 / 再生医学 / 歯科矯正学 |
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| Outline of Final Research Achievements |
The result of this study is as follows, 1) We succeeded in the induction from iPS cells of the mouse to the neural crest like cells. 2) TCP+NCLC group was shown to be stronger in a tendency to healing than TCP+MC3T3 group. 3) The CT value of the group of TCP+phosphorylated pullulan was higher than other groups. The results suggested that new bone prosthetic material may be realized by using iPS cell and phosphorylated pullulan.
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Report
(4 results)
Research Products
(25 results)
