Approach to a quantitative method for evaluating the facial characteristics of patients with congenital anomalies for analyzing genome to phenome correlations
| Project/Area Number |
15K11340
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Orthodontics/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
TSUJI Michiko 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (90345281)
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| Co-Investigator(Kenkyū-buntansha) |
馬場 祥行 東京医科歯科大学, 歯学部, 非常勤講師 (70251535)
鈴木 聖一 東京医科歯科大学, 大学院医歯学総合研究科, 准教授 (90187732)
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| Project Period (FY) |
2015-10-21 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2015: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 先天異常疾患 / バーチャルフェイス / 定量的評価 / 非接触型三次元顔面形状計測 / 特異的顔貌 |
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| Outline of Final Research Achievements |
The purpose of this study was to quantitatively define the facial characteristics of patients with congenital anomalies by constructing a virtual face and comparing it to that of non-syndromic subjects. The congenital anomaly group composed of Turner syndrome patients and the control group composed of non-syndromic subjects. Three-dimensional photographs were acquired from both groups using a non-contact three dimensions digitizer. Homologous models were constructed from the three-dimensional photographs using a three-dimensional shape analysis software.
From the homologous model, virtual faces of the two groups were compared by the averaged face technique. It revealed that in the congenital anomaly group, more protrusion of the subnasale to the upper lip, lower height of the apex of nose, deeper mentolabial sulcus and more mandibular retrusion particularly mentum region.
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Report
(4 results)
Research Products
(23 results)
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[Presentation] Maxillofacial morphology of 4 cases of Marfan-related diseases in mixed dentition stage2016
Author(s)
BabaY, Komazaki Y, Miyamoto J, Ogura K, Ahiko N, Baba Y, Tsuji M, Moriyama
Organizer
The 49th Annual Scientific Congress, Korean Association of Orthodontists
Place of Presentation
COEX, Seoul, Korea
Year and Date
2016-10-07
Related Report
Int'l Joint Research
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