NLRP3 Inflammasome in onset periodotitis
| Project/Area Number |
15K11396
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Periodontology
|
|---|
| Research Institution | Nagasaki University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 歯周炎 / T細胞 / アタッチメントロス / インフラマソーム / 歯石結晶 |
|---|
| Outline of Final Research Achievements |
The onset and progression of periodontitis involve bacterial infection and the immune response. T cells function in the immune response and reportedly induce bone resorption in inflammatory bone loss. However, the exact role of T cells in periodontal destruction remains unclear. Using our experimental model of periodontitis, we aimed to investigate the influence of T cells on periodontal destruction.
|
Report
(4 results)
Research Products
(6 results)
-
-
-
[Presentation] 炎症性骨吸収における破骨細胞形成へのT細胞と骨膜構成細胞の関与2017
Author(s)
小林 弘樹, 鵜飼 孝, 中村 弘隆, 高森（藏本） 明子, 高森 雄三, 山下 恭徳, 泉 聡史, 小山 美香, 白石 千秋, 吉村 篤利, 原 宜興
Organizer
第146回日本歯科保存学会2017年度春季学術大会
Related Report
-
-
-
