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The observational study about cognitive function in patients with chronic kidney disease.

Research Project

Project/Area Number 15K11589
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Clinical nursing
Research InstitutionSaga University (2016-2017)
Kyushu University (2015)

Principal Investigator

Yoshida Hisako  佐賀大学, 医学部, 特任准教授 (60437788)

Co-Investigator(Kenkyū-buntansha) 鶴屋 和彦  奈良県立医科大学, 医学部, 教授 (20372740)
藤崎 毅一郎  九州大学, 大学病院, その他 (10444811)
Project Period (FY) 2015-10-21 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords慢性腎臓病 / 認知機能 / Quality of life / 脳MRI / QOL / 認知機能検査
Outline of Final Research Achievements

We performed three type of examination: cognitive function test, quality of life (QOL) questionaire research, and brain atrophy via magnetic resonance images, for patients with chronic kidney disease (CKD).We evaluated the change value of QOL score per 2 years of CKD patiens using analysis of covariance adjusted baseline score and determined the change value per year of gray matter volume of them.We compared these values among CKD stages: 3, 4, 5, maintenance hemodialysis,and peritoneal dialysis patients. In addition, we will analyse the association between QOL, brain atrophy and cognitive function. Now, we are writing the paper to publish our report.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2018 2017 2015

All Journal Article (2 results) (of which Open Access: 1 results,  Peer Reviewed: 1 results) Presentation (4 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] The utility of a network-based clustering method for dimension reduction of imaging and non-imaging biomarkers predictive of Alzheimer’s disease2018

    • Author(s)
      Hisako Yoshida, Atsushi Kawaguchi, Fumio Yamashita, Kazuhiko Tsuruya
    • Journal Title

      Scientific Report

      Volume: 8 Issue: 1 Pages: 1-10

    • DOI

      10.1038/s41598-018-21118-1

    • Related Report
      2017 Annual Research Report
    • Open Access
  • [Journal Article] Clinical Significance of Fronto-Temporal Gray Matter Atrophy in Executive Dysfunction in Patients with Chronic Kidney Disease: The VCOHP Study.2015

    • Author(s)
      Tsuruya K, Yoshida H, Haruyama N, Fujisaki K, Hirakata H, Kitazono T.
    • Journal Title

      PLoS One

      Volume: 2015 Issue: 12 Pages: e0143706-e0143706

    • DOI

      10.1371/journal.pone.0143706

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] Difference in Consideration of Patient Eligibility for Peritoneal Dialysis between Nephrologists and Other Medical Staffs; using a Conjoint Analysis2018

    • Author(s)
      Hisako Yoshida, Kazuhiko Tsuruya
    • Organizer
      ISN Frontiers Meeting 2018
    • Related Report
      2017 Annual Research Report
  • [Presentation] 腹膜炎発症と腹膜透析継続との関連2017

    • Author(s)
      吉田寿子,鶴屋和彦
    • Organizer
      第60回日本腎臓学会学術総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 医師とコメディカルスタッフにおける腹膜透析の適格基準についての認識の相違 - コンジョイント分析を用いたWebアンケートより2017

    • Author(s)
      吉田寿子,鶴屋和彦
    • Organizer
      第23回日本腹膜透析医学会学術集会・総会
    • Related Report
      2017 Annual Research Report
  • [Presentation] The possibility of faster progression of brain atrophy in patients on peritoneal dialysis compared with hemodialysis2015

    • Author(s)
      Tsuruya K, Yoshida H, Kitazono T
    • Organizer
      48th Annual Meeting of the American Society of Nephrology
    • Place of Presentation
      San Diego, CA, USA
    • Year and Date
      2015-11-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research

URL: 

Published: 2015-10-21   Modified: 2019-03-29  

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