| Project/Area Number |
15K12136
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Life / Health / Medical informatics
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Research Collaborator |
KAWAMATA Ibuki
TSUZAWA Masaru
Keitel Cervantes-Salguero
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 分子ロボティクス / 電場駆動型ロコモーション / 電場駆動型分子計算素子 / DNAコンピュータ |
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| Outline of Final Research Achievements |
Aiming at developing (1) a molecular moving body digitally stepping in one direction in response to an applied electric field and (2) molecular computing elements able to perform logic operation in response to an applied electric field, electric response properties of DNA is examined. (1) Using DNA Origami method, we developed a rotating vehicle with six feet with slight asymmetry and also developed an experimental system capable of single molecule observation under horizontal electric field. (2) An experimental system in which a DNA strand modified with gold nanoparticles is peeled off by applying an electric field is developed, and quantitative evaluation of the dehybridization behavior under electric field was conducted.
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