Diamagnetic rearangement of uric acid crystal structures causing gout
| Project/Area Number |
15K12511
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Hiroshima University |
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Principal Investigator |
Iwasaka Masakazu 広島大学, ナノデバイス・バイオ融合科学研究所, 教授 (90243922)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 磁場配向 / 尿酸結晶 / 反磁性 / 痛風 / 結晶構造 / 光反射 / 光計測 / 微結晶 / 再結晶化 / 結晶溶解 / 直流磁場 / 交流磁場 / 尿路結石 / 磁場効果 / 磁気回転運動 |
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| Outline of Final Research Achievements |
Magnetic and optical properties of uric acid crystals initiating gout were investigated for the development of a new possible diagnostics for gout. We studied the effect of magnetic fields on structure of uric acid crystals. In addition, the relation between light reflection by micro-crystals and magnetic orientation was evaluated for the realization of optical diagnostics of crystallization. As a model system, a dynamic change of the crystal structure from amorphous to plate-like crystals was exhibited. Magnetic orientation of the plate-like crystals right after applying a 500 mT magnetic field was observed. The observed distinct anisotropy of uric acid crystals is useful for the remote detection of the uric acid crystallization and its shape.
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Report
(3 results)
Research Products
(25 results)
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[Book] 磁気便覧2016
Author(s)
岩坂正和 他
Total Pages
888
Publisher
丸善出版
Related Report
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