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Development of innovative intravascular liquid embolization using light curing method

Research Project

Project/Area Number 15K12535
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Biomedical engineering/Biomaterial science and engineering
Research InstitutionThe University of Tokyo

Principal Investigator

Oishi Masamichi  東京大学, 生産技術研究所, 技術専門職員 (70396901)

Co-Investigator(Kenkyū-buntansha) 早川 基治  藤田保健衛生大学, 医学部, 准教授 (40319257)
Co-Investigator(Renkei-kenkyūsha) OSHIMA Marie  東京大学, 大学院情報学環, 教授 (40242127)
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords動脈瘤 / 塞栓術 / 光硬化樹脂 / 血管内治療
Outline of Final Research Achievements

In this study, in the intravascular treatment method called "embolization" which fills an embolic material inside of the aneurysm to prevent rupture, we tried to develop "light curing embolization" using light-curing liquid resin instead of conventional metal coil. As a necessary condition for the safe and efficient embolization, hydrodynamic investigations such as pulling back the embolus material injected from the catheter and preventing outflow of the embolus material to the downstream due to blood flow, and the optical and photochemical design which control light curing of the embolic material were conducted. To realize this method, we aim to achieve versatility that can apply to various sizes and shapes of aneurysm and conduct the experiment under the imaging environment in actual surgery using image diagnostic equipment.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (2 results)

All 2015 Other

All Presentation (1 results) (of which Int'l Joint Research: 1 results) Remarks (1 results)

  • [Presentation] Development of an Integrated 1D-0D Simulation System for Patient-Specific2015

    • Author(s)
      Masaharu Kobayashi, Atsushi Harada, Hao Zhang, Shigeki Yamada, Masamichi Oishi, Marie Oshima
    • Organizer
      Interdisciplinary Cerebrovascular Symposium 2015
    • Place of Presentation
      Gold Coast, Australia
    • Year and Date
      2015-11-13
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 東京大学生産技術研究所・大島研究室ホームページ

    • URL

      http://www.oshimalab.iis.u-tokyo.ac.jp

    • Related Report
      2016 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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