Development of a novel VEP pad contributing to accuracy improvement and popularization of intraoperative VEP monitoring

• Project/Area Number: 15K12559
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Medical systems
• Research Institution: Kumamoto University
• Principal Investigator: Yamakawa Toshitaka 熊本大学, 大学院先導機構, 助教 (60510419)
• Co-Investigator(Kenkyū-buntansha): 丸田 雄一 山口大学, 医学部, 特別医学研究員 (30543970)
• Co-Investigator(Renkei-kenkyūsha): NIWAYAMA Masatsugu 静岡大学, 工学研究科, 准教授 (40334958) ; INOUE Takao 山口大学, 医学部付属病院, 講師 (80513225)
• Project Period (FY): 2015-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: フレキシブルプリント基板回路 / 視覚誘発電位 / 術中生理検査 / 術中視覚誘発電位モニタリング / 半側視野刺激 / 電子デバイス・機器 / 脳・神経 / リハビリテーション / モニタリング

Outline of Final Research Achievements

Visual evoked potential (VEP) is one of the intraoperative monitoring methods to avoid severe postoperative complications such as loss of vision, and is evoked by applying
flush light stimulus to the patients retina. In this project, a novel VEP pad which is flexible, disposable, and capable of applying complicated lighting patterns was designed with optical simulation using the Monte-Calro method. The fabricated VEP pad showed capability of visual hemifield stimulation and pupil detection even under eyelid closure.

Research Products

• [Journal Article] 運転中の能動的行為によるドライバの覚醒維持効果と運転安全性 (2017)
  • Author(s): 伊部達朗, 平岡敏洋, 阿部恵里花, 藤原幸一, 山川俊貴
  • Journal Title: 自動車技術会論文集 Volume: 48(2) Pages: 463-469
  • NAID: 130006734236
  • Peer Reviewed
• [Journal Article] Epileptic Seizure Prediction Based on Multivariate Statistical Process Control of Heart Rate Variability Features (2015)
  • Author(s): K. Fujiwara, M. Miyajima, T. Yamakawa, E. Abe, Y. Suzuki, Y. Sawada, M. Kano, T. Maehara, K. Ohta, T. Sasai-Sakuma, T. Sasano, M. Matsuura, and E. Matsushima
  • Journal Title: IEEE Transactions on Biomedical Engineering Volume: PP(99) Issue: 6 Pages: 1-11
  • DOI: 10.1109/tbme.2015.2512276
  • Peer Reviewed / Open Access
• [Presentation] Wakefulness Keeping Support System for Drivers Based on Game Using Body Movement and Voice Input Command (2016)
  • Author(s): Toshihiro Hiraoka, Ibe Tatsuro, Erika Abe, Koichi Fujiwara, Toshitaka Yamakawa
  • Organizer: IEEE EMBC 2016
  • Place of Presentation: オーランド（米国）
  • Year and Date: 2016-08-16
  • Int'l Joint Research
• [Presentation] Individuality Reduction in Heart Rate Variability for Drowsy Driving Detection (2016)
  • Author(s): Koichi Fujiwara, Erika Abe, Toshitaka Yamakawa, Manabu Kano
  • Organizer: IEEE EMBC 2016
  • Place of Presentation: オーランド（米国）
  • Year and Date: 2016-08-16
  • Int'l Joint Research
• [Presentation] Real-Time Epileptic Seizure Prediction System Employing a Wearable HRV Telemeter and a Smartphone (2016)
  • Author(s): Miho Miyajima, Toshitaka Yamakawa, Koichi Fujiwara, Yuriko Sawada, Yoko Suzuki, Erika Abe, Manabu Kano, Satsuki Watanabe, Yoshiko Murata, Yutaka Watanabe, Taketoshi Maehara, Eisuke Matsushima
  • Organizer: IEEE EMBC 2016
  • Place of Presentation: オーランド（米国）
  • Year and Date: 2016-08-16
  • Int'l Joint Research
• [Presentation] 術中VEPモニタリングの精度向上を目指したフレキシブル光刺激デバイスの開発 (2015)
  • Author(s): 中村凜太郎、山川俊貴、井上貴雄、平山祐哉、丸田雄一、鈴木倫保、坂田聡、上田裕市
  • Organizer: SSI2015
  • Place of Presentation: 函館
  • Year and Date: 2015-11-18